Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.267
Description:Flavonoid 3',5'-methyltransferase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.267
BRENDA Enzyme Link: BRENDA 2.1.1.267
KEGG Enzyme Link: KEGG2.1.1.267
BioCyc Enzyme Link: BioCyc 2.1.1.267
ExPASy Enzyme Link: ExPASy2.1.1.267
EC2PDB Enzyme Link: EC2PDB 2.1.1.267
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.267
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.267
IntEnz Enzyme Link: IntEnz 2.1.1.267
MEDLINE Enzyme Link: MEDLINE 2.1.1.267
MSA:

2.1.1.267;

Phylogenetic Tree:

2.1.1.267;

Uniprot:
M-CSA:
RHEA:55336 a 5'-hydroxy-3'-methoxyflavone + S-adenosyl-L-methionine = a 3',5'-dimethoxyflavone + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Characterization of a Vitis vinifera cv. Cabernet Sauvignon 3',5'-O-methyltransferase showing strong preference for anthocyanins and glycosylated flavonols.Lücker J, Martens S, Lund ST2010 Sep20580386
A novel cation-dependent O-methyltransferase involved in anthocyanin methylation in grapevine.Hugueney P, Provenzano S, Verriès C, Ferrandino A, Meudec E, Batelli G, Merdinoglu D, Cheynier V, Schubert A, Ageorges A2009 Aug19525322
A flavonol O-methyltransferase from Catharanthus roseus performing two sequential methylations.Cacace S, Schröder G, Wehinger E, Strack D, Schmidt J, Schröder J2003 Jan12482447

RHEA:55332 a 3'-hydroxyflavone + S-adenosyl-L-methionine = a 3'-methoxyflavone + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Characterization of a Vitis vinifera cv. Cabernet Sauvignon 3',5'-O-methyltransferase showing strong preference for anthocyanins and glycosylated flavonols.Lücker J, Martens S, Lund ST2010 Sep20580386
A novel cation-dependent O-methyltransferase involved in anthocyanin methylation in grapevine.Hugueney P, Provenzano S, Verriès C, Ferrandino A, Meudec E, Batelli G, Merdinoglu D, Cheynier V, Schubert A, Ageorges A2009 Aug19525322
A flavonol O-methyltransferase from Catharanthus roseus performing two sequential methylations.Cacace S, Schröder G, Wehinger E, Strack D, Schmidt J, Schröder J2003 Jan12482447

RHEA:25633 laricitrin + S-adenosyl-L-methionine = H(+) + S-adenosyl-L-homocysteine + syringetin
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
A novel cation-dependent O-methyltransferase involved in anthocyanin methylation in grapevine.Hugueney P, Provenzano S, Verriès C, Ferrandino A, Meudec E, Batelli G, Merdinoglu D, Cheynier V, Schubert A, Ageorges A2009 Aug19525322
A flavonol O-methyltransferase from Catharanthus roseus performing two sequential methylations.Cacace S, Schröder G, Wehinger E, Strack D, Schmidt J, Schröder J2003 Jan12482447

RHEA:25629 myricetin + S-adenosyl-L-methionine = H(+) + laricitrin + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
A novel cation-dependent O-methyltransferase involved in anthocyanin methylation in grapevine.Hugueney P, Provenzano S, Verriès C, Ferrandino A, Meudec E, Batelli G, Merdinoglu D, Cheynier V, Schubert A, Ageorges A2009 Aug19525322
A flavonol O-methyltransferase from Catharanthus roseus performing two sequential methylations.Cacace S, Schröder G, Wehinger E, Strack D, Schmidt J, Schröder J2003 Jan12482447