EC number:2.1.1.272

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.272
Description:Cobalt-factor III methyltransferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.272
BRENDA Enzyme Link: BRENDA 2.1.1.272
KEGG Enzyme Link: KEGG2.1.1.272
BioCyc Enzyme Link: BioCyc 2.1.1.272
ExPASy Enzyme Link: ExPASy2.1.1.272
EC2PDB Enzyme Link: EC2PDB 2.1.1.272
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.272
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.272
IntEnz Enzyme Link: IntEnz 2.1.1.272
MEDLINE Enzyme Link: MEDLINE 2.1.1.272

EC number:2.1.1.272

MSA:

2.1.1.272;
Phylogenetic Tree:

2.1.1.272;
Uniprot:
M-CSA:
RHEA:36155 AH2 + Co(II)-factor III + S-adenosyl-L-methionine = A + Co-precorrin-4 + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[*:5]=[C;H0;+0:6](-[*:7])-[CH2;+0:8]-[*:9]-[C;H0;+0:10]1=[C;H0;+0:11](-[*:12])-[C;H0;+0:13]2=[N+;H0:14]3-[C;H0;+0:15]-1=[CH;+0:16]-[c;H0;+0:17]1:[c;H0;+0:18](-[*:19]):[c;H0;+0:20](-[*:21]-[*:22]-[OH;+0:23]):[c;H0;+0:24]4:[n;H0;+0:25]:1-[*:26]-31-[*:27]3=[*:28](-[CH;+0:29]=[C;H0;+0:30]5-[N;H0;+0:31]-1-[C;H0;+0:32](=[CH;+0:33]-2)-[CH;+0:34](-[CH2;+0:35]-[CH2;+0:36]-[C;H0;+0:37](=[O;H0;+0:38])-[OH;+0:39])-[C;H0;+0:40]-5(-[CH3;+0:41])-[CH2;+0:42]-[C;H0;+0:43](=[O;H0;+0:44])-[OH;+0:45])-[CH;+0:46](-[*:47])-[C;H0;+0:48](-[*:49])(-[CH3;+0:50])-[C;H0;+0:51]-3=[C;H0;+0:52]-4-[*:53]>>[*:1]-[S;H0;+0:2]-[*:3].[*:5]=[C;H0;+0:6](-[*:7])-[CH2;+0:50]-[c;H0;+0:33]1:[c;H0;+0:13](-[CH2;+0:11]-[*:12]):[c;H0;+0:30]2:[n;H0;+0:31]3:[c;H0;+0:32]:1-[CH;+0:34]=[C;H0;+0:35]1-[CH;+0:36](-[CH2;+0:41]-[CH2;+0:40]-[C;H0;+0:42](=[O;H0;+0:38])-[OH;+0:39])-[C;H0;+0:10](-[CH3;+0:37])(-[*:9]-[C;H0;+0:8](=[O;H0;+0:44])-[OH;+0:45])-[C;H0;+0:15]4=[N+;H0:14]-1-[*:26]-31-[*:27]3=[*:28](-[CH2;+0:29]-2)-[C;H0;+0:46](-[*:47])(-[CH3;+0:4])-[C;H0;+0:48](-[*:49])=[C;H0;+0:51]-3-[C;H0;+0:24]23-[CH;+0:52](-[*:53])-[O;H0;+0:23]-[*:22]-[*:21]-[C;H0;+0:20]-2(-[CH3;+0:43])-[CH;+0:18](-[*:19])-[C;H0;+0:17](=[CH;+0:16]-4)-[N;H0;+0:25]-1-3
Reaction
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References

TitleAuthorsDatePubMed ID
Characterization of the enzyme CbiH60 involved in anaerobic ring contraction of the cobalamin (vitamin B12) biosynthetic pathway.Moore SJ, Biedendieck R, Lawrence AD, Deery E, Howard MJ, Rigby SE, Warren MJ2013 Jan 423155054