EC number:2.1.1.281

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.281
Description:Phenylpyruvate C(3)-methyltransferase.
Alternative Name: Phenylpyruvate methyltransferase.
Phenylpyruvate C-beta-methyltransferase.
Cath: 1.10.10.10; 3.40.50.150;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.281
BRENDA Enzyme Link: BRENDA 2.1.1.281
KEGG Enzyme Link: KEGG2.1.1.281
BioCyc Enzyme Link: BioCyc 2.1.1.281
ExPASy Enzyme Link: ExPASy2.1.1.281
EC2PDB Enzyme Link: EC2PDB 2.1.1.281
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.281
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.281
IntEnz Enzyme Link: IntEnz 2.1.1.281
MEDLINE Enzyme Link: MEDLINE 2.1.1.281

EC number:2.1.1.281

MSA:

2.1.1.281;
Phylogenetic Tree:

2.1.1.281;
Uniprot:
M-CSA:
RHEA:36623 3-phenylpyruvate + S-adenosyl-L-methionine = (3S)-2-oxo-3-phenylbutanoate + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[CH2;+0:2]-[*:3].[*:4]-[S+;H0:5](-[*:6])-[CH3;+0:7]>>[*:1]-[CH;+0:2](-[*:3])-[CH3;+0:7].[*:4]-[S;H0;+0:5]-[*:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
In vitro characterization of enzymes involved in the synthesis of nonproteinogenic residue (2S,3S)-beta-methylphenylalanine in glycopeptide antibiotic mannopeptimycin.Huang YT, Lyu SY, Chuang PH, Hsu NS, Li YS, Chan HC, Huang CJ, Liu YC, Wu CJ, Yang WB, Li TL2009 Oct 1219731276
O-Methylation of flavonoid substrates by a partially purified enzyme from soybean cell suspension cultures.Poulton JE, Hahlbrock K, Grisebach H1977 Apr 3018099
Functional expression of an Arabidopsis cDNA clone encoding a flavonol 3'-O-methyltransferase and characterization of the gene product.Muzac I, Wang J, Anzellotti D, Zhang H, Ibrahim RK2000 Mar 1510700397