Enzyme

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EC Tree
     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.291
Description:(R,S)-reticuline 7-O-methyltransferase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.291
BRENDA Enzyme Link: BRENDA 2.1.1.291
KEGG Enzyme Link: KEGG2.1.1.291
BioCyc Enzyme Link: BioCyc 2.1.1.291
ExPASy Enzyme Link: ExPASy2.1.1.291
EC2PDB Enzyme Link: EC2PDB 2.1.1.291
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.291
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.291
IntEnz Enzyme Link: IntEnz 2.1.1.291
MEDLINE Enzyme Link: MEDLINE 2.1.1.291
MSA:

2.1.1.291;

Phylogenetic Tree:

2.1.1.291;

Uniprot:
M-CSA:
RHEA:38907 (R)-reticuline + S-adenosyl-L-methionine = (R)-laudanine + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The roles of latex and the vascular bundle in morphine biosynthesis in the opium poppy, Papaver somniferum.Weid M, Ziegler J, Kutchan TM2004 Sep 2115353584
(R,S)-Reticuline 7-O-methyltransferase and (R,S)-norcoclaurine 6-O-methyltransferase of Papaver somniferum - cDNA cloning and characterization of methyl transfer enzymes of alkaloid biosynthesis in opium poppy.Ounaroon A, Decker G, Schmidt J, Lottspeich F, Kutchan TM2003 Dec14675446

RHEA:10444 (S)-reticuline + S-adenosyl-L-methionine = (S)-laudanine + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The roles of latex and the vascular bundle in morphine biosynthesis in the opium poppy, Papaver somniferum.Weid M, Ziegler J, Kutchan TM2004 Sep 2115353584
(R,S)-Reticuline 7-O-methyltransferase and (R,S)-norcoclaurine 6-O-methyltransferase of Papaver somniferum - cDNA cloning and characterization of methyl transfer enzymes of alkaloid biosynthesis in opium poppy.Ounaroon A, Decker G, Schmidt J, Lottspeich F, Kutchan TM2003 Dec14675446