Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.294
Description:3-phospho-methyltransferase.
Cath: 1.10.510.10; 3.30.200.20; 3.40.50.150;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.294
BRENDA Enzyme Link: BRENDA 2.1.1.294
KEGG Enzyme Link: KEGG2.1.1.294
BioCyc Enzyme Link: BioCyc 2.1.1.294
ExPASy Enzyme Link: ExPASy2.1.1.294
EC2PDB Enzyme Link: EC2PDB 2.1.1.294
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.294
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.294
IntEnz Enzyme Link: IntEnz 2.1.1.294
MEDLINE Enzyme Link: MEDLINE 2.1.1.294
MSA:

2.1.1.294;

Phylogenetic Tree:

2.1.1.294;

Uniprot:
M-CSA:
RHEA:36639 3-O-phospho-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-di-trans,octa-cis-undecaprenol + S-adenosyl-L-methionine = 3-O-methylphospho-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenol + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
In vitro reconstruction of the chain termination reaction in biosynthesis of the Escherichia coli O9a O-polysaccharide: the chain-length regulator, WbdD, catalyzes the addition of methyl phosphate to the non-reducing terminus of the growing glycan.Clarke BR, Richards MR, Greenfield LK, Hou D, Lowary TL, Whitfield C2011 Dec 221990359
Coordination of polymerization, chain termination, and export in assembly of the Escherichia coli lipopolysaccharide O9a antigen in an ATP-binding cassette transporter-dependent pathway.Clarke BR, Greenfield LK, Bouwman C, Whitfield C2009 Oct 3019734145
Nonreducing terminal modifications determine the chain length of polymannose O antigens of Escherichia coli and couple chain termination to polymer export via an ATP-binding cassette transporter.Clarke BR, Cuthbertson L, Whitfield C2004 Aug 2015184370