Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.295
Description:2-methyl-6-phytyl-1,4-hydroquinone methyltransferase.
Alternative Name: MPBQ/MSBQ methyltransferase.
2-methyl-6-solanyl-1,4-hydroquinone methyltransferase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.295
BRENDA Enzyme Link: BRENDA 2.1.1.295
KEGG Enzyme Link: KEGG2.1.1.295
BioCyc Enzyme Link: BioCyc 2.1.1.295
ExPASy Enzyme Link: ExPASy2.1.1.295
EC2PDB Enzyme Link: EC2PDB 2.1.1.295
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.295
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.295
IntEnz Enzyme Link: IntEnz 2.1.1.295
MEDLINE Enzyme Link: MEDLINE 2.1.1.295
MSA:

2.1.1.295;

Phylogenetic Tree:

2.1.1.295;

Uniprot:
M-CSA:
RHEA:38007 6-geranylgeranyl-2-methylbenzene-1,4-diol + S-adenosyl-L-methionine = 6-geranylgeranyl-2,3-dimethylbenzene-1,4-diol + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[*:5]:[cH;+0:6]:[*:7]>>[*:1]-[S;H0;+0:2]-[*:3].[*:5]:[c;H0;+0:6](:[*:7])-[CH3;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Current opinions on the functions of tocopherol based on the genetic manipulation of tocopherol biosynthesis in plants.Li Y, Wang Z, Sun X, Tang K2008 Sep18844774
Highly divergent methyltransferases catalyze a conserved reaction in tocopherol and plastoquinone synthesis in cyanobacteria and photosynthetic eukaryotes.Cheng Z, Sattler S, Maeda H, Sakuragi Y, Bryant DA, DellaPenna D2003 Oct14508009

RHEA:37999 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol + S-adenosyl-L-methionine = H(+) + plastoquinol-9 + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[*:5]:[cH;+0:6]:[*:7]>>[*:1]-[S;H0;+0:2]-[*:3].[*:5]:[c;H0;+0:6](:[*:7])-[CH3;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Highly divergent methyltransferases catalyze a conserved reaction in tocopherol and plastoquinone synthesis in cyanobacteria and photosynthetic eukaryotes.Cheng Z, Sattler S, Maeda H, Sakuragi Y, Bryant DA, DellaPenna D2003 Oct14508009
The role of 2-methyl-6-phytylbenzoquinone methyltransferase in determining tocopherol composition in Synechocystis sp. PCC6803.Shintani DK, Cheng Z, DellaPenna D2002 Jan 3011821038

RHEA:37979 2-methyl-6-phytyl-1,4-benzene-1,4-diol + S-adenosyl-L-methionine = 2,3-dimethyl-6-phytylbenzene-1,4-diol + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[*:5]:[cH;+0:6]:[*:7]>>[*:1]-[S;H0;+0:2]-[*:3].[*:5]:[c;H0;+0:6](:[*:7])-[CH3;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Engineering vitamin E content: from Arabidopsis mutant to soy oil.Van Eenennaam AL, Lincoln K, Durrett TP, Valentin HE, Shewmaker CK, Thorne GM, Jiang J, Baszis SR, Levering CK, Aasen ED, Hao M, Stein JC, Norris SR, Last RL2003 Dec14630966
Highly divergent methyltransferases catalyze a conserved reaction in tocopherol and plastoquinone synthesis in cyanobacteria and photosynthetic eukaryotes.Cheng Z, Sattler S, Maeda H, Sakuragi Y, Bryant DA, DellaPenna D2003 Oct14508009
The role of 2-methyl-6-phytylbenzoquinone methyltransferase in determining tocopherol composition in Synechocystis sp. PCC6803.Shintani DK, Cheng Z, DellaPenna D2002 Jan 3011821038