EC number:2.1.1.305

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.305
Description:8-demethyl-8-alpha-L-rhamnosyl tetracenomycin-C 2'-O-methyltransferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.305
BRENDA Enzyme Link: BRENDA 2.1.1.305
KEGG Enzyme Link: KEGG2.1.1.305
BioCyc Enzyme Link: BioCyc 2.1.1.305
ExPASy Enzyme Link: ExPASy2.1.1.305
EC2PDB Enzyme Link: EC2PDB 2.1.1.305
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.305
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.305
IntEnz Enzyme Link: IntEnz 2.1.1.305
MEDLINE Enzyme Link: MEDLINE 2.1.1.305

EC number:2.1.1.305

MSA:

2.1.1.305;
Phylogenetic Tree:

2.1.1.305;
Uniprot:
M-CSA:
RHEA:41540 8-demethyl-8-alpha-L-rhamnosyl-tetracenomycin C + S-adenosyl-L-methionine = 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Deoxysugar methylation during biosynthesis of the antitumor polyketide elloramycin by Streptomyces olivaceus. Characterization of three methyltransferase genes.Patallo EP, Blanco G, Fischer C, Brana AF, Rohr J, Mendez C, Salas JA2001 Jun 111376004