EC number:2.1.1.311

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.311
Description:25S rRNA (cytosine(2278)-C(5))-methyltransferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.311
BRENDA Enzyme Link: BRENDA 2.1.1.311
KEGG Enzyme Link: KEGG2.1.1.311
BioCyc Enzyme Link: BioCyc 2.1.1.311
ExPASy Enzyme Link: ExPASy2.1.1.311
EC2PDB Enzyme Link: EC2PDB 2.1.1.311
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.311
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.311
IntEnz Enzyme Link: IntEnz 2.1.1.311
MEDLINE Enzyme Link: MEDLINE 2.1.1.311

EC number:2.1.1.311

MSA:

2.1.1.311;
Phylogenetic Tree:

2.1.1.311;
Uniprot:
M-CSA:
RHEA:43180 cytidine(2278) in 25S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(2278) in 25S rRNA + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[*:5]:[cH;+0:6]:[*:7]>>[*:1]-[S;H0;+0:2]-[*:3].[*:5]:[c;H0;+0:6](:[*:7])-[CH3;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively.Sharma S, Yang J, Watzinger P, Kötter P, Entian KD2013 Oct23913415