EC number:2.1.1.313

Enzyme

Download
EC Tree
     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.313
Description:25S rRNA (uracil(2634)-N(3))-methyltransferase.

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.
PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.313
BRENDA Enzyme Link: BRENDA 2.1.1.313
KEGG Enzyme Link: KEGG2.1.1.313
BioCyc Enzyme Link: BioCyc 2.1.1.313
ExPASy Enzyme Link: ExPASy2.1.1.313
EC2PDB Enzyme Link: EC2PDB 2.1.1.313
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.313
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.313
IntEnz Enzyme Link: IntEnz 2.1.1.313
MEDLINE Enzyme Link: MEDLINE 2.1.1.313

EC number:2.1.1.313

MSA:

2.1.1.313;
Phylogenetic Tree:

2.1.1.313;
Uniprot:
M-CSA:
RHEA:54588 S-adenosyl-L-methionine + uridine in 25S rRNA = H(+) + N(3)-methyluridine in 25S rRNA + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[*:5]:[nH;+0:6]:[*:7]>>[*:1]-[S;H0;+0:2]-[*:3].[*:5]:[n;H0;+0:6](:[*:7])-[CH3;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction
RHEA:43188 S-adenosyl-L-methionine + uridine(2634) in 25S rRNA = H(+) + N(3)-methyluridine(2634) in 25S rRNA + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[*:5]:[nH;+0:6]:[*:7]>>[*:1]-[S;H0;+0:2]-[*:3].[*:5]:[n;H0;+0:6](:[*:7])-[CH3;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Identification of novel methyltransferases, Bmt5 and Bmt6, responsible for the m3U methylations of 25S rRNA in Saccharomyces cerevisiae.Sharma S, Yang J, Düttmann S, Watzinger P, Kötter P, Entian KD2014 Mar24335083