EC number:2.1.1.315

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.315
Description:27-O-demethylrifamycin SV methyltransferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.315
BRENDA Enzyme Link: BRENDA 2.1.1.315
KEGG Enzyme Link: KEGG2.1.1.315
BioCyc Enzyme Link: BioCyc 2.1.1.315
ExPASy Enzyme Link: ExPASy2.1.1.315
EC2PDB Enzyme Link: EC2PDB 2.1.1.315
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.315
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.315
IntEnz Enzyme Link: IntEnz 2.1.1.315
MEDLINE Enzyme Link: MEDLINE 2.1.1.315

EC number:2.1.1.315

MSA:

2.1.1.315;
Phylogenetic Tree:

2.1.1.315;
Uniprot:
M-CSA:
RHEA:44740 27-O-demethylrifamycin SV + S-adenosyl-L-methionine = H(+) + rifamycin SV + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Isolation and characterization of 27-O-demethylrifamycin SV methyltransferase provides new insights into the post-PKS modification steps during the biosynthesis of the antitubercular drug rifamycin B by Amycolatopsis mediterranei S699.Xu J, Mahmud T, Floss HG2003 Mar 1512623077