EC number:2.1.1.317

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.317
Description:Sphingolipid C(9)-methyltransferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.317
BRENDA Enzyme Link: BRENDA 2.1.1.317
KEGG Enzyme Link: KEGG2.1.1.317
BioCyc Enzyme Link: BioCyc 2.1.1.317
ExPASy Enzyme Link: ExPASy2.1.1.317
EC2PDB Enzyme Link: EC2PDB 2.1.1.317
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.317
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.317
IntEnz Enzyme Link: IntEnz 2.1.1.317
MEDLINE Enzyme Link: MEDLINE 2.1.1.317

EC number:2.1.1.317

MSA:

2.1.1.317;
Phylogenetic Tree:

2.1.1.317;
Uniprot:
M-CSA:
RHEA:46804 a (4E,8E)-4-sphinga-4,8-dienine ceramide + S-adenosyl-L-methionine = a 9-methyl-(4E,8E)-sphinga-4,8-dienine ceramide + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[*:5]=[CH;+0:6]-[*:7]>>[*:1]-[S;H0;+0:2]-[*:3].[*:5]=[C;H0;+0:6](-[*:7])-[CH3;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Candida albicans sphingolipid C9-methyltransferase is involved in hyphal elongation.Oura T, Kajiwara S2010 Apr20019081
Sphingolipid C-9 methyltransferases are important for growth and virulence but not for sensitivity to antifungal plant defensins in Fusarium graminearum.Ramamoorthy V, Cahoon EB, Thokala M, Kaur J, Li J, Shah DM2009 Feb19028992
Identification of fungal sphingolipid C9-methyltransferases by phylogenetic profiling.Ternes P, Sperling P, Albrecht S, Franke S, Cregg JM, Warnecke D, Heinz E2006 Mar 316339149