Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.324
Description:dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose N,N-dimethyltransferase.
Alternative Name: TDP-4-amino-2,3,6-trideoxy-D-glucose N,N-dimethyltransferase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.324
BRENDA Enzyme Link: BRENDA 2.1.1.324
KEGG Enzyme Link: KEGG2.1.1.324
BioCyc Enzyme Link: BioCyc 2.1.1.324
ExPASy Enzyme Link: ExPASy2.1.1.324
EC2PDB Enzyme Link: EC2PDB 2.1.1.324
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.324
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.324
IntEnz Enzyme Link: IntEnz 2.1.1.324
MEDLINE Enzyme Link: MEDLINE 2.1.1.324
MSA:

2.1.1.324;

Phylogenetic Tree:

2.1.1.324;

Uniprot:
M-CSA:
RHEA:49148 dTDP-4-amino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose + 2 S-adenosyl-L-methionine = dTDP-alpha-D-forosamine + 2 H(+) + 2 S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[NH2;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6].[*:7]-[S+;H0:8](-[*:9])-[CH3;+0:10]>>[*:1]-[N;H0;+0:2](-[CH3;+0:6])-[CH3;+0:10].[*:3]-[S;H0;+0:4]-[*:5].[*:7]-[S;H0;+0:8]-[*:9]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
In vitro characterization of the enzymes involved in TDP-D-forosamine biosynthesis in the spinosyn pathway of Saccharopolyspora spinosa.Hong L, Zhao Z, Melançon CE 3rd, Zhang H, Liu HW2008 Apr 918345667