EC number:2.1.1.325

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.325
Description:Juvenile hormone-III synthase.
Alternative Name: Juvenile hormone acid methyltransferase.
Farnesoic acid methyltransferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.325
BRENDA Enzyme Link: BRENDA 2.1.1.325
KEGG Enzyme Link: KEGG2.1.1.325
BioCyc Enzyme Link: BioCyc 2.1.1.325
ExPASy Enzyme Link: ExPASy2.1.1.325
EC2PDB Enzyme Link: EC2PDB 2.1.1.325
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.325
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.325
IntEnz Enzyme Link: IntEnz 2.1.1.325
MEDLINE Enzyme Link: MEDLINE 2.1.1.325

EC number:2.1.1.325

MSA:

2.1.1.325;
Phylogenetic Tree:

2.1.1.325;
Uniprot:
M-CSA:
RHEA:43720 juvenile hormone III carboxylate + S-adenosyl-L-methionine = juvenile hormone III + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Juvenile hormone synthesis: "esterify then epoxidize" or "epoxidize then esterify"? Insights from the structural characterization of juvenile hormone acid methyltransferase.Defelipe LA, Dolghih E, Roitberg AE, Nouzova M, Mayoral JG, Noriega FG, Turjanski AG2011 Apr21195763
Juvenile hormone acid O-methyltransferase in Drosophila melanogaster.Niwa R, Niimi T, Honda N, Yoshiyama M, Itoyama K, Kataoka H, Shinoda T2008 Jul18549957
Juvenile hormone acid methyltransferase: a key regulatory enzyme for insect metamorphosis.Shinoda T, Itoyama K2003 Oct 1414530389
RHEA:43700 (2E,6E)-farnesoate + S-adenosyl-L-methionine = methyl (2E,6E)-farnesoate + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Juvenile hormone acid O-methyltransferase in Drosophila melanogaster.Niwa R, Niimi T, Honda N, Yoshiyama M, Itoyama K, Kataoka H, Shinoda T2008 Jul18549957
Juvenile hormone acid methyltransferase: a key regulatory enzyme for insect metamorphosis.Shinoda T, Itoyama K2003 Oct 1414530389