EC number:2.1.1.326
| ID: | 2.1.1.326 |
|---|---|
| Description: | N-acetyl-demethylphosphinothricin P-methyltransferase. |
| Alternative Name: |
P-methylase. |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 2.1.1.326 |
| BRENDA Enzyme Link: | BRENDA 2.1.1.326 |
| KEGG Enzyme Link: | KEGG2.1.1.326 |
| BioCyc Enzyme Link: | BioCyc 2.1.1.326 |
| ExPASy Enzyme Link: | ExPASy2.1.1.326 |
| EC2PDB Enzyme Link: | EC2PDB 2.1.1.326 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.1.1.326 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.1.1.326 |
| IntEnz Enzyme Link: | IntEnz 2.1.1.326 |
| MEDLINE Enzyme Link: | MEDLINE 2.1.1.326 |
EC number:2.1.1.326
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:49128 | AH2 + N-acetyl-demethyl-L-phosphinothricin + 2 S-adenosyl-L-methionine = 5'-deoxyadenosine + A + 2 H(+) + L-methionine + N-acetyl-L-phosphinothricin + S-adenosyl-L-homocysteine |
| RULE(radius=1) | [*:1]-[PH;+0:2](=[*:3])-[*:4].[*:5]-[S+;H0:6](-[*:7])-[CH2;+0:8]-[*:9].[*:10]-[S+;H0:11](-[*:12])-[CH3;+0:13]>>[*:9]-[CH3;+0:8].[*:1]-[P;H0;+0:2](=[*:3])(-[*:4])-[CH3;+0:13].[*:10]-[S;H0;+0:11]-[*:12].[*:5]-[S;H0;+0:6]-[*:7] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Sequence of a P-methyltransferase-encoding gene isolated from a bialaphos-producing Streptomyces hygroscopicus. | Hidaka T, Hidaka M, Kuzuyama T, Seto H | 1995 May 26 | 7789803 |
| Investigation of enzymatic C-P bond formation using multiple quantum HCP nuclear magnetic resonance spectroscopy. | Hu K, Werner WJ, Allen KD, Wang SC | 2015 Apr | 25594737 |
| Spectroscopic characterization and mechanistic investigation of P-methyl transfer by a radical SAM enzyme from the marine bacterium Shewanella denitrificans OS217. | Allen KD, Wang SC | 2014 Dec | 25224746 |
| In vitro phosphinate methylation by PhpK from Kitasatospora phosalacinea. | Werner WJ, Allen KD, Hu K, Helms GL, Chen BS, Wang SC | 2011 Oct 25 | 21950770 |
| Studies on the biosynthesis of bialaphos (SF-1293) 12. C-P bond formation mechanism of bialaphos: discovery of a P-methylation enzyme. | Kamigiri K, Hidaka T, Imai S, Murakami T, Seto H | 1992 May | 1624380 |