Enzyme

Download
EC Tree
     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.335
Description:4-amino-anhydrotetracycline N(4)-methyltransferase.

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.335
BRENDA Enzyme Link: BRENDA 2.1.1.335
KEGG Enzyme Link: KEGG2.1.1.335
BioCyc Enzyme Link: BioCyc 2.1.1.335
ExPASy Enzyme Link: ExPASy2.1.1.335
EC2PDB Enzyme Link: EC2PDB 2.1.1.335
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.335
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.335
IntEnz Enzyme Link: IntEnz 2.1.1.335
MEDLINE Enzyme Link: MEDLINE 2.1.1.335
MSA:

2.1.1.335;

Phylogenetic Tree:

2.1.1.335;

Uniprot:
M-CSA:
RHEA:50768 4-methylamino-4-dedimethylamino-anhydrotetracycline + S-adenosyl-L-methionine = anhydrotetracycline + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[NH;+0:2]-[*:3].[*:4]-[S+;H0:5](-[*:6])-[CH3;+0:7]>>[*:1]-[N;H0;+0:2](-[*:3])-[CH3;+0:7].[*:4]-[S;H0;+0:5]-[*:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Identifying the minimal enzymes required for anhydrotetracycline biosynthesis.Zhang W, Watanabe K, Cai X, Jung ME, Tang Y, Zhan J2008 May 1418422316

RHEA:50764 4-amino-4-dedimethylamino-anhydrotetracycline + S-adenosyl-L-methionine = 4-methylamino-4-dedimethylamino-anhydrotetracycline + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[NH2;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[NH;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Identifying the minimal enzymes required for anhydrotetracycline biosynthesis.Zhang W, Watanabe K, Cai X, Jung ME, Tang Y, Zhan J2008 May 1418422316