| ID: | 2.1.1.335 |
|---|---|
| Description: | 4-amino-anhydrotetracycline N(4)-methyltransferase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 2.1.1.335 |
| BRENDA Enzyme Link: | BRENDA 2.1.1.335 |
| KEGG Enzyme Link: | KEGG2.1.1.335 |
| BioCyc Enzyme Link: | BioCyc 2.1.1.335 |
| ExPASy Enzyme Link: | ExPASy2.1.1.335 |
| EC2PDB Enzyme Link: | EC2PDB 2.1.1.335 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.1.1.335 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.1.1.335 |
| IntEnz Enzyme Link: | IntEnz 2.1.1.335 |
| MEDLINE Enzyme Link: | MEDLINE 2.1.1.335 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:50768 | 4-methylamino-4-dedimethylamino-anhydrotetracycline + S-adenosyl-L-methionine = anhydrotetracycline + H(+) + S-adenosyl-L-homocysteine |
| RULE(radius=1) | [*:1]-[NH;+0:2]-[*:3].[*:4]-[S+;H0:5](-[*:6])-[CH3;+0:7]>>[*:1]-[N;H0;+0:2](-[*:3])-[CH3;+0:7].[*:4]-[S;H0;+0:5]-[*:6] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Identifying the minimal enzymes required for anhydrotetracycline biosynthesis. | Zhang W, Watanabe K, Cai X, Jung ME, Tang Y, Zhan J | 2008 May 14 | 18422316 |
| RHEA:50764 | 4-amino-4-dedimethylamino-anhydrotetracycline + S-adenosyl-L-methionine = 4-methylamino-4-dedimethylamino-anhydrotetracycline + H(+) + S-adenosyl-L-homocysteine |
| RULE(radius=1) | [*:1]-[NH2;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[NH;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Identifying the minimal enzymes required for anhydrotetracycline biosynthesis. | Zhang W, Watanabe K, Cai X, Jung ME, Tang Y, Zhan J | 2008 May 14 | 18422316 |