EC number:2.1.1.34

Enzyme

Download
EC Tree
     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.34
Description:tRNA (guanosine(18)-2'-O)-methyltransferase.
Alternative Name: tRNA (Gm18) methyltransferase.
tRNA (Gm18) 2'-O-methyltransferase.
Cath: 3.40.1280.10;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.
PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.34
BRENDA Enzyme Link: BRENDA 2.1.1.34
KEGG Enzyme Link: KEGG2.1.1.34
BioCyc Enzyme Link: BioCyc 2.1.1.34
ExPASy Enzyme Link: ExPASy2.1.1.34
EC2PDB Enzyme Link: EC2PDB 2.1.1.34
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.34
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.34
IntEnz Enzyme Link: IntEnz 2.1.1.34
MEDLINE Enzyme Link: MEDLINE 2.1.1.34

EC number:2.1.1.34

MSA:

2.1.1.34;
Phylogenetic Tree:

2.1.1.34;
Uniprot:
M-CSA:
RHEA:20077 guanosine(18) in tRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(18) in tRNA + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Substrate recognition of tRNA (Guanosine-2'-)-methyltransferase from Thermus thermophilus HB27.Hori H, Yamazaki N, Matsumoto T, Watanabe Y, Ueda T, Nishikawa K, Kumagai I, Watanabe K1998 Oct 29748240
The in vitro synthesis of 2'-omethylguanosine and 2-methylthio 6N (gamma,gamma, dimethylallyl) adenosine in transfer RNA of Escherichia coli.Gefter ML1969 Aug 74898378