EC number:2.1.1.346

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.346
Description:U6 snRNA m(6)A methyltransferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.346
BRENDA Enzyme Link: BRENDA 2.1.1.346
KEGG Enzyme Link: KEGG2.1.1.346
BioCyc Enzyme Link: BioCyc 2.1.1.346
ExPASy Enzyme Link: ExPASy2.1.1.346
EC2PDB Enzyme Link: EC2PDB 2.1.1.346
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.346
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.346
IntEnz Enzyme Link: IntEnz 2.1.1.346
MEDLINE Enzyme Link: MEDLINE 2.1.1.346

EC number:2.1.1.346

MSA:

2.1.1.346;
Phylogenetic Tree:

2.1.1.346;
Uniprot:
M-CSA:
RHEA:52808 adenosine in U6 snRNA + S-adenosyl-L-methionine = H(+) + N(6)-methyladenosine in U6 snRNA + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[NH2;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[NH;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The U6 snRNA m<sup>6</sup>A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention.Pendleton KE, Chen B, Liu K, Hunter OV, Xie Y, Tu BP, Conrad NK2017 May 1828525753