EC number:2.1.1.46
| ID: | 2.1.1.46 |
|---|---|
| Description: | Isoflavone 4'-O-methyltransferase. |
| Cath: | 1.10.10.10; 3.40.50.150; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.1.1.46 |
| BRENDA Enzyme Link: | BRENDA 2.1.1.46 |
| KEGG Enzyme Link: | KEGG2.1.1.46 |
| BioCyc Enzyme Link: | BioCyc 2.1.1.46 |
| ExPASy Enzyme Link: | ExPASy2.1.1.46 |
| EC2PDB Enzyme Link: | EC2PDB 2.1.1.46 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.1.1.46 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.1.1.46 |
| IntEnz Enzyme Link: | IntEnz 2.1.1.46 |
| MEDLINE Enzyme Link: | MEDLINE 2.1.1.46 |
| RHEA:31739 | a 4'-hydroxyisoflavone + S-adenosyl-L-methionine = a 4'-methoxyisoflavone + H(+) + S-adenosyl-L-homocysteine |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification and properties of a S-adenosylmethionine: isoflavone 4'-O-methyltransferase from cell suspension cultures of Cicer arietinum L. | Wengenmayer H, Ebel J, Grisebach H | 1974 Dec 16 | 4452353 |
| Structural basis for dual functionality of isoflavonoid O-methyltransferases in the evolution of plant defense responses. | Liu CJ, Deavours BE, Richard SB, Ferrer JL, Blount JW, Huhman D, Dixon RA, Noel JP | 2006 Dec | 17172354 |
| cDNA cloning and biochemical characterization of S-adenosyl-L-methionine: 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase, a critical enzyme of the legume isoflavonoid phytoalexin pathway. | Akashi T, Sawada Y, Shimada N, Sakurai N, Aoki T, Ayabe S | 2003 Feb | 12610212 |