EC number:2.1.1.47
| ID: | 2.1.1.47 |
|---|---|
| Description: | Indolepyruvate C-methyltransferase. |
| Alternative Name: |
Indolepyruvic acid methyltransferase. Indolepyruvate methyltransferase. Indolepyruvate 3-methyltransferase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.1.1.47 |
| BRENDA Enzyme Link: | BRENDA 2.1.1.47 |
| KEGG Enzyme Link: | KEGG2.1.1.47 |
| BioCyc Enzyme Link: | BioCyc 2.1.1.47 |
| ExPASy Enzyme Link: | ExPASy2.1.1.47 |
| EC2PDB Enzyme Link: | EC2PDB 2.1.1.47 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.1.1.47 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.1.1.47 |
| IntEnz Enzyme Link: | IntEnz 2.1.1.47 |
| MEDLINE Enzyme Link: | MEDLINE 2.1.1.47 |
| RHEA:12112 | indole-3-pyruvate + S-adenosyl-L-methionine = (R)-3-(indol-3-yl)-2-oxobutanoate + H(+) + S-adenosyl-L-homocysteine |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[*:3].[*:4]-[S+;H0:5](-[*:6])-[CH3;+0:7]>>[*:1]-[CH;+0:2](-[*:3])-[CH3;+0:7].[*:4]-[S;H0;+0:5]-[*:6] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Isolation and characterization of tryptophan transaminase and indolepyruvate C-methyltransferase. Enzymes involved in indolmycin biosynthesis in Streptomyces griseus. | Speedie MK, Hornemann U, Floss HG | 1975 Oct 10 | 809439 |
| Demonstration of a C-methylating enzyme in cell free extracts of indolmycin-producing Streptomyces griseus. | Hornemann U, Speedie MK, Hurley LH, Floss HG | 1970 May 22 | 5490210 |
| The biosynthesis of indolmycin. | Hornemann U, Hurley LH, Speedie MK, Floss HG | 1971 Jun 16 | 5095271 |
| In vitro reconstitution of indolmycin biosynthesis reveals the molecular basis of oxazolinone assembly. | Du YL, Alkhalaf LM, Ryan KS | 2015 Mar 3 | 25730866 |