EC number:2.1.1.5
| ID: | 2.1.1.5 |
|---|---|
| Description: | Betaine--homocysteine S-methyltransferase. |
| Cath: | 3.20.20.330; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.1.1.5 |
| BRENDA Enzyme Link: | BRENDA 2.1.1.5 |
| KEGG Enzyme Link: | KEGG2.1.1.5 |
| BioCyc Enzyme Link: | BioCyc 2.1.1.5 |
| ExPASy Enzyme Link: | ExPASy2.1.1.5 |
| EC2PDB Enzyme Link: | EC2PDB 2.1.1.5 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.1.1.5 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.1.1.5 |
| IntEnz Enzyme Link: | IntEnz 2.1.1.5 |
| MEDLINE Enzyme Link: | MEDLINE 2.1.1.5 |
| RHEA:22336 | betaine + L-homocysteine = L-methionine + N,N-dimethylglycine |
| RULE(radius=1) | [*:1]-[N+;H0:2](-[*:3])(-[*:4])-[CH3;+0:5].[*:6]-[SH;+0:7]>>[*:1]-[N;H0;+0:2](-[*:3])-[*:4].[*:6]-[S;H0;+0:7]-[CH3;+0:5] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Dissecting the catalytic mechanism of betaine-homocysteine S-methyltransferase by use of intrinsic tryptophan fluorescence and site-directed mutagenesis. | Castro C, Gratson AA, Evans JC, Jiracek J, Collinsová M, Ludwig ML, Garrow TA | 2004 May 11 | 15122900 |
| Betaine-homocysteine methyltransferase: zinc in a distorted barrel. | Evans JC, Huddler DP, Jiracek J, Castro C, Millian NS, Garrow TA, Ludwig ML | 2002 Sep | 12220488 |