EC number:2.1.1.56
| ID: | 2.1.1.56 |
|---|---|
| Description: | mRNA (guanine-N(7)-)-methyltransferase. |
| Alternative Name: |
Messenger RNA guanine 7-methyltransferase. Messenger ribonucleate guanine 7-methyltransferase. Guanine-7-methyltransferase. |
| Cath: | 1.10.10.930; 1.10.260.90; 1.10.8.970; 1.20.1280.260; 3.20.100.10; 3.20.100.20; 3.30.387.10; 3.30.470.140; 3.30.67.10; 3.30.70.2840; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.1.1.56 |
| BRENDA Enzyme Link: | BRENDA 2.1.1.56 |
| KEGG Enzyme Link: | KEGG2.1.1.56 |
| BioCyc Enzyme Link: | BioCyc 2.1.1.56 |
| ExPASy Enzyme Link: | ExPASy2.1.1.56 |
| EC2PDB Enzyme Link: | EC2PDB 2.1.1.56 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.1.1.56 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.1.1.56 |
| IntEnz Enzyme Link: | IntEnz 2.1.1.56 |
| MEDLINE Enzyme Link: | MEDLINE 2.1.1.56 |
| RHEA:11220 | a 5'-(5'-triphosphoguanosine)-(purine-ribonucleotide)-[mRNA] + S-adenosyl-L-methionine = a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleotide)-[mRNA] + S-adenosyl-L-homocysteine |
| RULE(radius=1) | [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[*:5]:[n;H0;+0:6]:[*:7]>>[*:1]-[S;H0;+0:2]-[*:3].[*:5]:[n+;H0:6](:[*:7])-[CH3;+0:4] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Methylation and capping of RNA polymerase II primary transcripts by HeLa nuclear homogenates. | Groner Y, Gilboa E, Aviv H | 1978 Mar 21 | 629955 |
| mRNA capping: biological functions and applications. | Ramanathan A, Robb GB, Chan SH | 2016 Sep 19 | 27317694 |
| Modification of RNA by mRNA guanylyltransferase and mRNA (guanine-7-)methyltransferase from vaccinia virions. | Martin SA, Moss B | 1975 Dec 25 | 1194287 |
| Purification of mRNA guanylyltransferase and mRNA (guanine-7-) methyltransferase from vaccinia virions. | Martin SA, Paoletti E, Moss B | 1975 Dec 25 | 1194286 |
| Modification of the 5'-terminus of mRNA by soluble guanylyl and methyl transferases from vaccinia virus. | Ensinger MJ, Martin SA, Paoletti E, Moss B | 1975 Jul | 1058472 |