EC number:2.1.1.69

Enzyme

Download
EC Tree
     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.69
Description:5-hydroxyfuranocoumarin 5-O-methyltransferase.
Alternative Name: Furanocoumarin 5-O-methyltransferase.
Furanocoumarin 5-methyltransferase.
BMT.
Bergaptol O-methyltransferase.
Bergaptol methyltransferase.
Bergaptol 5-O-methyltransferase.

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.
PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.69
BRENDA Enzyme Link: BRENDA 2.1.1.69
KEGG Enzyme Link: KEGG2.1.1.69
BioCyc Enzyme Link: BioCyc 2.1.1.69
ExPASy Enzyme Link: ExPASy2.1.1.69
EC2PDB Enzyme Link: EC2PDB 2.1.1.69
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.69
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.69
IntEnz Enzyme Link: IntEnz 2.1.1.69
MEDLINE Enzyme Link: MEDLINE 2.1.1.69

EC number:2.1.1.69

MSA:

2.1.1.69;
Phylogenetic Tree:

2.1.1.69;
Uniprot:
M-CSA:
RHEA:24894 5-hydroxyxanthotoxin + S-adenosyl-L-methionine = isopimpinellin + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction
RHEA:18861 a 5-hydroxyfurocoumarin + S-adenosyl-L-methionine = a 5-methoxyfurocoumarin + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Furanocoumarin biosynthesis in Ammi majus L. Cloning of bergaptol O-methyltransferase.Hehmann M, Lukacin R, Ekiert H, Matern U2004 Mar15009205
RHEA:11808 bergaptol + S-adenosyl-L-methionine = bergapten + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Furanocoumarin biosynthesis in Ammi majus L. Cloning of bergaptol O-methyltransferase.Hehmann M, Lukacin R, Ekiert H, Matern U2004 Mar15009205