EC number:2.1.1.70
| ID: | 2.1.1.70 |
|---|---|
| Description: | 8-hydroxyfuranocoumarin 8-O-methyltransferase. |
| Alternative Name: |
XMT. Xanthotoxol 8-O-methyltransferase. Furanocoumarin 8-O-methyl-transferase. Furanocoumarin 8-methyltransferase. |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 2.1.1.70 |
| BRENDA Enzyme Link: | BRENDA 2.1.1.70 |
| KEGG Enzyme Link: | KEGG2.1.1.70 |
| BioCyc Enzyme Link: | BioCyc 2.1.1.70 |
| ExPASy Enzyme Link: | ExPASy2.1.1.70 |
| EC2PDB Enzyme Link: | EC2PDB 2.1.1.70 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.1.1.70 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.1.1.70 |
| IntEnz Enzyme Link: | IntEnz 2.1.1.70 |
| MEDLINE Enzyme Link: | MEDLINE 2.1.1.70 |
| RHEA:21244 | an 8-hydroxyfurocoumarin + S-adenosyl-L-methionine = 8-methoxyfurocoumarin + H(+) + S-adenosyl-L-homocysteine |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| O-methyltransferases of furanocoumarin biosynthesis. | Thompson HJ, Sharma SK, Brown SA | 1978 Jun | 28084 |
| Separation of the S-adenosylmethionine: 5- and 8-hydroxyfuranocoumarin O-methyltransferases of Ruta graveolens L. by general ligand affinity chromatography. | Sharma SK, Garrett JM, Brown SA | 1979 May-Jun | 156999 |
| Furanocoumarin biosynthesis in Ammi majus L. Cloning of bergaptol O-methyltransferase. | Hehmann M, Lukacin R, Ekiert H, Matern U | 2004 Mar | 15009205 |
| RHEA:17901 | S-adenosyl-L-methionine + xanthotoxol = H(+) + S-adenosyl-L-homocysteine + xanthotoxin |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| O-methyltransferases of furanocoumarin biosynthesis. | Thompson HJ, Sharma SK, Brown SA | 1978 Jun | 28084 |
| Separation of the S-adenosylmethionine: 5- and 8-hydroxyfuranocoumarin O-methyltransferases of Ruta graveolens L. by general ligand affinity chromatography. | Sharma SK, Garrett JM, Brown SA | 1979 May-Jun | 156999 |
| Furanocoumarin biosynthesis in Ammi majus L. Cloning of bergaptol O-methyltransferase. | Hehmann M, Lukacin R, Ekiert H, Matern U | 2004 Mar | 15009205 |