Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.86
Description:Tetrahydromethanopterin S-methyltransferase.
Alternative Name: Tetrahydromethanopterin methyltransferase.
N(5)-methyltetrahydromethanopterin--coenzyme M methyltransferase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.86
BRENDA Enzyme Link: BRENDA 2.1.1.86
KEGG Enzyme Link: KEGG2.1.1.86
BioCyc Enzyme Link: BioCyc 2.1.1.86
ExPASy Enzyme Link: ExPASy2.1.1.86
EC2PDB Enzyme Link: EC2PDB 2.1.1.86
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.86
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.86
IntEnz Enzyme Link: IntEnz 2.1.1.86
MEDLINE Enzyme Link: MEDLINE 2.1.1.86
MSA:

2.1.1.86;

Phylogenetic Tree:

2.1.1.86;

Uniprot:
M-CSA:
RHEA:53492 5-methyl-5,6,7,8-tetrahydromethanopterin + coenzyme M + 2 Na(+)(in) = 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M + 2 Na(+)(out)
RULE(radius=1) [*:1]-[N;H0;+0:2](-[*:3])-[CH3;+0:4].[*:5]-[SH;+0:6]>>[*:1]-[NH;+0:2]-[*:3].[*:5]-[S;H0;+0:6]-[CH3;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Purification and properties of N5-methyltetrahydromethanopterin:coenzyme M methyltransferase from Methanobacterium thermoautotrophicum.Gärtner P, Ecker A, Fischer R, Linder D, Fuchs G, Thauer RK1993 Apr 18477726
The energetics and sodium-ion dependence of N5-methyltetrahydromethanopterin:coenzyme M methyltransferase studied with cob(I)alamin as methyl acceptor and methylcob(III)alamin as methyl donor.Weiss DS, Gärtner P, Thauer RK1994 Dec 157813469
The energy conserving N5-methyltetrahydromethanopterin:coenzyme M methyltransferase complex from Methanobacterium thermoautotrophicum is composed of eight different subunits.Harms U, Weiss DS, Gärtner P, Linder D, Thauer RK1995 Mar 157737157
Tetrahydromethanopterin methyltransferase, a component of the methane synthesizing complex of Methanobacterium thermoautotrophicum.Sauer FD1986 Apr 293085670
Role of the fused corrinoid/methyl transfer protein CmtA during CO-dependent growth of Methanosarcina acetivorans.Vepachedu VR, Ferry JG2012 Aug22636775
The Na(+)-translocating methyltransferase complex from methanogenic archaea.Gottschalk G, Thauer RK2001 May 111248186