Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.2 Hydroxymethyl-, formyl- and related transferases
ID:2.1.2.9
Description:Methionyl-tRNA formyltransferase.
Alternative Name: transformylase.
N(10)-formyltetrahydrofolic-methionyl-transfer ribonucleic
Methionyl-tRNA transformylase.
Methionyl-tRNA Met formyltransferase.
Methionyl-transfer RNA transformylase.
Methionyl-transfer ribonucleic transformylase.
Methionyl-transfer ribonucleate methyltransferase.
Methionyl ribonucleic formyltransferase.
Formylmethionyl-transfer ribonucleic synthetase.
Prosite: PDOC00319;
PDB:
PDBScop
Cath: 1.10.220.140; 1.10.287.10; 1.10.730.10; 1.20.1050.10; 1.20.1050.110; 3.40.50.620; 2.170.220.10; 2.20.28.20; 2.40.50.140; 3.40.30.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.2.9
BRENDA Enzyme Link: BRENDA 2.1.2.9
KEGG Enzyme Link: KEGG2.1.2.9
BioCyc Enzyme Link: BioCyc 2.1.2.9
ExPASy Enzyme Link: ExPASy2.1.2.9
EC2PDB Enzyme Link: EC2PDB 2.1.2.9
ExplorEnz Enzyme Link: ExplorEnz 2.1.2.9
PRIAM enzyme-specific profiles Link: PRIAM 2.1.2.9
IntEnz Enzyme Link: IntEnz 2.1.2.9
MEDLINE Enzyme Link: MEDLINE 2.1.2.9
MSA:

2.1.2.9;

Phylogenetic Tree:

2.1.2.9;

Uniprot:
M-CSA:
RHEA:24380 (6S)-10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = (6S)-5,6,7,8-tetrahydrofolate + H(+) + N-formyl-L-methionyl-tRNA(fMet)
RULE(radius=1) [*:1]-[NH2;+0:2].[*:3]=[CH;+0:4]-[N;H0;+0:5](-[*:6])-[*:7]>>[*:6]-[NH;+0:5]-[*:7].[*:3]=[CH;+0:4]-[NH;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Methionyl soluble ribonucleic acid transformylase. I. Purification and partial characterization.Dickerman HW, Steers E Jr, Redfield BG, Weissbach H1967 Apr 105337045