EC number:2.1.3.12
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.1 Transferring one-carbon groups |
| 2.1.3 Carboxy- and carbamoyltransferases |
| ID: | 2.1.3.12 |
|---|---|
| Description: | Decarbamoylnovobiocin carbamoyltransferase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.1.3.12 |
| BRENDA Enzyme Link: | BRENDA 2.1.3.12 |
| KEGG Enzyme Link: | KEGG2.1.3.12 |
| BioCyc Enzyme Link: | BioCyc 2.1.3.12 |
| ExPASy Enzyme Link: | ExPASy2.1.3.12 |
| EC2PDB Enzyme Link: | EC2PDB 2.1.3.12 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.1.3.12 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.1.3.12 |
| IntEnz Enzyme Link: | IntEnz 2.1.3.12 |
| MEDLINE Enzyme Link: | MEDLINE 2.1.3.12 |
| RHEA:36659 | carbamoyl phosphate + descarbamoylnovobiocin = novobiocin + phosphate |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:4]-[*:5].[*:6]-[OH;+0:7]>>[*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:7]-[*:6].[*:5]-[OH;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The crystal structure of the novobiocin biosynthetic enzyme NovP: the first representative structure for the TylF O-methyltransferase superfamily. | Gómez García I, Stevenson CE, Usón I, Freel Meyers CL, Walsh CT, Lawson DM | 2010 Jan 15 | 19857499 |
| Characterization of NovP and NovN: completion of novobiocin biosynthesis by sequential tailoring of the noviosyl ring. | Freel Meyers CL, Oberthür M, Xu H, Heide L, Kahne D, Walsh CT | 2004 Jan | 14694473 |