EC number:2.1.4.1
| ID: | 2.1.4.1 |
|---|---|
| Description: | Glycine amidinotransferase. |
| Alternative Name: |
L-arginine:glycine amidinotransferase. |
| Cath: | 3.75.10.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.1.4.1 |
| BRENDA Enzyme Link: | BRENDA 2.1.4.1 |
| KEGG Enzyme Link: | KEGG2.1.4.1 |
| BioCyc Enzyme Link: | BioCyc 2.1.4.1 |
| ExPASy Enzyme Link: | ExPASy2.1.4.1 |
| EC2PDB Enzyme Link: | EC2PDB 2.1.4.1 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.1.4.1 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.1.4.1 |
| IntEnz Enzyme Link: | IntEnz 2.1.4.1 |
| MEDLINE Enzyme Link: | MEDLINE 2.1.4.1 |
| RHEA:13201 | glycine + L-arginine = guanidinoacetate + L-ornithine |
| RULE(radius=1) | [*:1]-[NH2;+0:2].[*:3]=[C;H0;+0:4](-[*:5])-[NH;+0:6]-[*:7]>>[*:7]-[NH2;+0:6].[*:3]=[C;H0;+0:4](-[*:5])-[NH;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Crystal structure and mechanism of human L-arginine:glycine amidinotransferase: a mitochondrial enzyme involved in creatine biosynthesis. | Humm A, Fritsche E, Steinbacher S, Huber R | 1997 Jun 16 | 9218780 |
| Recombinant expression and isolation of human L-arginine:glycine amidinotransferase and identification of its active-site cysteine residue. | Humm A, Fritsche E, Mann K, Göhl M, Huber R | 1997 Mar 15 | 9148748 |
| Synthesis of neuroactive guanidino compounds by rat kidney L-arginine: glycine amidinotransferase. | Watanabe Y, Van Pilsum JF, Yokoi I, Mori A | 1994 | 8035648 |
| The effect of growth hormone and thyroxine on the amount of L-arginine:glycine amidinotransferase in kidneys of hypophysectomized rats. Purification and some properties of rat kidney transamidinase. | McGuire DM, Tormanen CD, Segal IS, Van Pilsum JF | 1980 Feb 10 | 6766137 |
| The purification and characterization of human kidney L-arginine:glycine amidinotransferase. | Gross MD, Eggen MA, Simon AM, Van Pilsum JF | 1986 Dec | 3800397 |
| A novel superfamily of enzymes that catalyze the modification of guanidino groups. | Shirai H, Blundell TL, Mizuguchi K | 2001 Aug | 11504612 |