Enzyme

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     2. Transferases
        2.10 Transferring molybdenum- or tungsten-containing groups
            2.10.1 Molybdenumtransferases or tungstentransferases with sulfide groups as acceptors
ID:2.10.1.1
Description:Molybdopterin molybdotransferase.
Cath: 3.40.980.10; 3.90.105.10; 2.170.190.11; 2.40.340.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.10.1.1
BRENDA Enzyme Link: BRENDA 2.10.1.1
KEGG Enzyme Link: KEGG2.10.1.1
BioCyc Enzyme Link: BioCyc 2.10.1.1
ExPASy Enzyme Link: ExPASy2.10.1.1
EC2PDB Enzyme Link: EC2PDB 2.10.1.1
ExplorEnz Enzyme Link: ExplorEnz 2.10.1.1
PRIAM enzyme-specific profiles Link: PRIAM 2.10.1.1
IntEnz Enzyme Link: IntEnz 2.10.1.1
MEDLINE Enzyme Link: MEDLINE 2.10.1.1
MSA:

2.10.1.1;

Phylogenetic Tree:

2.10.1.1;

Uniprot:
M-CSA:
RHEA:35047 adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-molybdopterin
RULE(radius=1) ([*:1]-[P;H0;+0:2](=[*:3])(-[*:4])-[O;H0;+0:5]-[*:6].[SH;+0:7]-[*:8]=[*:9]-[SH;+0:10]).[*:11]=[Mo;H0;+0:12](=[*:13])(-[OH;+0:14])-[OH;+0:15].[H+;H0:16]>>[*:6]-[OH;+0:5].([*:1]-[P;H0;+0:2](=[*:3])(-[*:4])-[OH;+0:14].[*:11]=[Mo;H0;+0:12]1(=[*:13])-[S;H0;+0:7]-[*:8]=[*:9]-[S;H0;+0:10]-1).[OH2;+0:15]
Reaction
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References

TitleAuthorsDatePubMed ID
The Mechanism of nucleotide-assisted molybdenum insertion into molybdopterin. A novel route toward metal cofactor assembly.Llamas A, Otte T, Multhaup G, Mendel RR, Schwarz G2006 Jul 716636046
In vitro molybdenum ligation to molybdopterin using purified components.Nichols JD, Rajagopalan KV2005 Mar 415632135