EC number:2.2.1.10

Enzyme

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     2. Transferases
        2.2 Transferring aldehyde or ketonic groups
            2.2.1 Transketolases and transaldolases
ID:2.2.1.10
Description:2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase.
Alternative Name: ADH synthase.
Cath: 3.20.20.70;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.2.1.10
BRENDA Enzyme Link: BRENDA 2.2.1.10
KEGG Enzyme Link: KEGG2.2.1.10
BioCyc Enzyme Link: BioCyc 2.2.1.10
ExPASy Enzyme Link: ExPASy2.2.1.10
EC2PDB Enzyme Link: EC2PDB 2.2.1.10
ExplorEnz Enzyme Link: ExplorEnz 2.2.1.10
PRIAM enzyme-specific profiles Link: PRIAM 2.2.1.10
IntEnz Enzyme Link: IntEnz 2.2.1.10
MEDLINE Enzyme Link: MEDLINE 2.2.1.10

EC number:2.2.1.10

MSA:

2.2.1.10;
Phylogenetic Tree:

2.2.1.10;
Uniprot:
M-CSA:
RHEA:25952 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate + L-aspartate 4-semialdehyde = 2,3-dioxopropyl phosphate + 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonate
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[CH;+0:4](-[*:5])-[OH;+0:6].[*:7]-[CH;+0:8]=[O;H0;+0:9]>>[*:7]-[CH;+0:8](-[OH;+0:9])-[CH;+0:2](-[*:1])-[*:3].[*:5]-[CH;+0:4]=[O;H0;+0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
MJ0400 from Methanocaldococcus jannaschii exhibits fructose-1,6-bisphosphate aldolase activity.Samland AK, Wang M, Sprenger GA2008 Apr18318840
Structure of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid synthase, a catalyst in the archaeal pathway for the biosynthesis of aromatic amino acids.Morar M, White RH, Ealick SE2007 Sep 1817713928
L-Aspartate semialdehyde and a 6-deoxy-5-ketohexose 1-phosphate are the precursors to the aromatic amino acids in Methanocaldococcus jannaschii.White RH2004 Jun 1515182204