EC number:2.2.1.7

Enzyme

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     2. Transferases
        2.2 Transferring aldehyde or ketonic groups
            2.2.1 Transketolases and transaldolases
ID:2.2.1.7
Description:1-deoxy-D-xylulose-5-phosphate synthase.
Alternative Name: DXP-synthase.
1-deoxyxylulose-5-phosphate synthase.
1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating).
Prosite: PDOC00635;
PDB:
PDBScop
Cath: 3.40.50.920; 3.40.50.970;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.2.1.7
BRENDA Enzyme Link: BRENDA 2.2.1.7
KEGG Enzyme Link: KEGG2.2.1.7
BioCyc Enzyme Link: BioCyc 2.2.1.7
ExPASy Enzyme Link: ExPASy2.2.1.7
EC2PDB Enzyme Link: EC2PDB 2.2.1.7
ExplorEnz Enzyme Link: ExplorEnz 2.2.1.7
PRIAM enzyme-specific profiles Link: PRIAM 2.2.1.7
IntEnz Enzyme Link: IntEnz 2.2.1.7
MEDLINE Enzyme Link: MEDLINE 2.2.1.7

EC number:2.2.1.7

MSA:

2.2.1.7;
Phylogenetic Tree:

2.2.1.7;
Uniprot:
M-CSA:
RHEA:12605 D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO2
RULE(radius=1) [*:1]-[CH;+0:2]=[O;H0;+0:3].[*:4]=[C;H0;+0:5](-[OH;+0:6])-[C;H0;+0:7](=[*:8])-[*:9].[H+;H0:10]>>[*:8]=[C;H0;+0:7](-[*:9])-[CH;+0:2](-[*:1])-[OH;+0:3].[*:4]=[C;H0;+0:5]=[O;H0;+0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Identification, cloning, purification, and enzymatic characterization of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate synthase.Bailey AM, Mahapatra S, Brennan PJ, Crick DC2002 Dec12499403