EC number:2.2.1.8
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.2 Transferring aldehyde or ketonic groups |
| 2.2.1 Transketolases and transaldolases |
| ID: | 2.2.1.8 |
|---|---|
| Description: | Fluorothreonine transaldolase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.2.1.8 |
| BRENDA Enzyme Link: | BRENDA 2.2.1.8 |
| KEGG Enzyme Link: | KEGG2.2.1.8 |
| BioCyc Enzyme Link: | BioCyc 2.2.1.8 |
| ExPASy Enzyme Link: | ExPASy2.2.1.8 |
| EC2PDB Enzyme Link: | EC2PDB 2.2.1.8 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.2.1.8 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.2.1.8 |
| IntEnz Enzyme Link: | IntEnz 2.2.1.8 |
| MEDLINE Enzyme Link: | MEDLINE 2.2.1.8 |
| RHEA:11748 | fluoroacetaldehyde + L-threonine = 4-fluoro-L-threonine + acetaldehyde |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[F;H0;+0:3].[*:4]-[CH3;+0:5]>>[*:4]-[CH2;+0:5]-[F;H0;+0:3].[*:1]-[CH3;+0:2] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| In vitro reconstituted biotransformation of 4-fluorothreonine from fluoride ion: application of the fluorinase. | Deng H, Cross SM, McGlinchey RP, Hamilton JT, O'Hagan D | 2008 Dec 22 | 19101471 |
| Fluorinated natural products: the biosynthesis of fluoroacetate and 4-fluorothreonine in Streptomyces cattleya. | Murphy CD, Schaffrath C, O'Hagan D | 2003 Jul | 12738270 |
| Identification of a PLP-Dependent Threonine Transaldolase: A Novel Enzyme Involved in 4-Fluorothreonine Biosynthesis in Streptomyces cattleya This work was supported by the Biotechnological and Biological Sciences Research Council and the University of St Andrews. | Murphy CD, O'Hagan D, Schaffrath C | 2001 Dec 3 | 12404452 |