EC number:2.2.1.9

Enzyme

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     2. Transferases
        2.2 Transferring aldehyde or ketonic groups
            2.2.1 Transketolases and transaldolases
ID:2.2.1.9
Description:synthase.
Alternative Name: SEPHCHC synthase.
Cath: 3.40.50.970; 3.40.50.1220; 3.40.50.1820;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.2.1.9
BRENDA Enzyme Link: BRENDA 2.2.1.9
KEGG Enzyme Link: KEGG2.2.1.9
BioCyc Enzyme Link: BioCyc 2.2.1.9
ExPASy Enzyme Link: ExPASy2.2.1.9
EC2PDB Enzyme Link: EC2PDB 2.2.1.9
ExplorEnz Enzyme Link: ExplorEnz 2.2.1.9
PRIAM enzyme-specific profiles Link: PRIAM 2.2.1.9
IntEnz Enzyme Link: IntEnz 2.2.1.9
MEDLINE Enzyme Link: MEDLINE 2.2.1.9

EC number:2.2.1.9

MSA:

2.2.1.9;
Phylogenetic Tree:

2.2.1.9;
Uniprot:
M-CSA:
RHEA:25593 2-oxoglutarate + H(+) + isochorismate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO2
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3])=[CH;+0:4]-[*:5].[*:6]=[C;H0;+0:7](-[OH;+0:8])-[C;H0;+0:9](=[*:10])-[*:11].[H+;H0:12]>>[*:1]-[CH;+0:2](-[*:3])-[CH;+0:4](-[*:5])-[C;H0;+0:9](=[*:10])-[*:11].[*:6]=[C;H0;+0:7]=[O;H0;+0:8]
Reaction
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References

TitleAuthorsDatePubMed ID
Menaquinone biosynthesis in Escherichia coli: identification of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate as a novel intermediate and re-evaluation of MenD activity.Jiang M, Cao Y, Guo ZF, Chen M, Chen X, Guo Z2007 Sep 2517760421