EC number:2.3.1.135
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.3 Acyltransferases |
| 2.3.1 Transferring groups other than aminoacyl groups |
| ID: | 2.3.1.135 |
|---|---|
| Description: | Phosphatidylcholine--retinol O-acyltransferase. |
| Alternative Name: |
Retinyl ester synthase. Lecithin-retinol acyltransferase. Lecithin--retinol acyltransferase. Lecithin retinol acyl transferase. |
| Cath: | 2.30.30.1140; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.3.1.135 |
| BRENDA Enzyme Link: | BRENDA 2.3.1.135 |
| KEGG Enzyme Link: | KEGG2.3.1.135 |
| BioCyc Enzyme Link: | BioCyc 2.3.1.135 |
| ExPASy Enzyme Link: | ExPASy2.3.1.135 |
| EC2PDB Enzyme Link: | EC2PDB 2.3.1.135 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.3.1.135 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.3.1.135 |
| IntEnz Enzyme Link: | IntEnz 2.3.1.135 |
| MEDLINE Enzyme Link: | MEDLINE 2.3.1.135 |
EC number:2.3.1.135
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:17469 | a 1,2-diacyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] = a 2-acyl-sn-glycero-3-phosphocholine + an all-trans-retinyl ester + apo--[retinol-binding protein] |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:4]-[*:5].[*:6]-[OH;+0:7]>>[*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:7]-[*:6].[*:5]-[OH;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Molecular and biochemical characterization of lecithin retinol acyltransferase. | Ruiz A, Winston A, Lim YH, Gilbert BA, Rando RR, Bok D | 1999 Feb 5 | 9920938 |
| Distribution of 11-cis LRAT, 11-cis RD and 11-cis REH in bovine retinal pigment epithelium membranes. | Mata NL, Tsin AT | 1998 Oct 2 | 9767084 |
| Retinol esterification in bovine retinal pigment epithelium: reversibility of lecithin:retinol acyltransferase. | Saari JC, Bredberg DL, Farrell DF | 1993 May 1 | 8489497 |
| Evidence for a lecithin-retinol acyltransferase activity in the rat small intestine. | MacDonald PN, Ong DE | 1988 Sep 5 | 3410848 |
| Lecithin:retinol acyltransferase in retinal pigment epithelial microsomes. | Saari JC, Bredberg DL | 1989 May 25 | 2722792 |