EC number:2.3.1.155
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.3 Acyltransferases |
| 2.3.1 Transferring groups other than aminoacyl groups |
| ID: | 2.3.1.155 |
|---|---|
| Description: | Acetyl-CoA C-myristoyltransferase. |
| Alternative Name: |
Myristoyl-CoA C-acetyltransferase. 3-oxopalmitoyl-CoA-CoA acetyltransferase. 3-oxopalmitoyl-CoA hydrolase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.3.1.155 |
| BRENDA Enzyme Link: | BRENDA 2.3.1.155 |
| KEGG Enzyme Link: | KEGG2.3.1.155 |
| BioCyc Enzyme Link: | BioCyc 2.3.1.155 |
| ExPASy Enzyme Link: | ExPASy2.3.1.155 |
| EC2PDB Enzyme Link: | EC2PDB 2.3.1.155 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.3.1.155 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.3.1.155 |
| IntEnz Enzyme Link: | IntEnz 2.3.1.155 |
| MEDLINE Enzyme Link: | MEDLINE 2.3.1.155 |
EC number:2.3.1.155
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:18161 | acetyl-CoA + tetradecanoyl-CoA = 3-oxohexadecanoyl-CoA + CoA |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](=[O;H0;+0:3])-[S;H0;+0:4]-[*:5].([*:6]-[CH2;+0:7]-[*:8].[*:9]-[CH3;+0:10])>>([*:6]-[C;H0;+0:7](-[*:8])=[O;H0;+0:3].[*:1]-[CH2;+0:2]-[CH2;+0:10]-[*:9]).[*:5]-[SH;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Substrate specificities of 3-oxoacyl-CoA thiolase A and sterol carrier protein 2/3-oxoacyl-CoA thiolase purified from normal rat liver peroxisomes. Sterol carrier protein 2/3-oxoacyl-CoA thiolase is involved in the metabolism of 2-methyl-branched fatty acids and bile acid intermediates. | Antonenkov VD, Van Veldhoven PP, Waelkens E, Mannaerts GP | 1997 Oct 10 | 9325339 |
| Molecular characterization of mitochondrial trifunctional protein deficiency: formation of the enzyme complex is important for stabilization of both alpha- and beta-subunits. | Ushikubo S, Aoyama T, Kamijo T, Wanders RJ, Rinaldo P, Vockley J, Hashimoto T | 1996 May | 8651282 |
| Mitochondrial trifunctional protein deficiency. Catalytic heterogeneity of the mutant enzyme in two patients. | Kamijo T, Wanders RJ, Saudubray JM, Aoyama T, Komiyama A, Hashimoto T | 1994 Apr | 8163672 |
| The mitochondrial long-chain trifunctional enzyme: 2-enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase and 3-oxoacyl-CoA thiolase. | Middleton B | 1994 May | 7958339 |
| Human liver long-chain 3-hydroxyacyl-coenzyme A dehydrogenase is a multifunctional membrane-bound beta-oxidation enzyme of mitochondria. | Carpenter K, Pollitt RJ, Middleton B | 1992 Mar 16 | 1550553 |
| Comparison of the stability and substrate specificity of purified peroxisomal 3-oxoacyl-CoA thiolases A and B from rat liver. | Antonenkov VD, Van Veldhoven PP, Waelkens E, Mannaerts GP | 1999 Feb 25 | 10064897 |