Enzyme

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     2. Transferases
        2.3 Acyltransferases
            2.3.1 Transferring groups other than aminoacyl groups
ID:2.3.1.162
Description:Taxadien-5-alpha-ol O-acetyltransferase.
Alternative Name: Taxadienol acetyltransferase.
Taxa-4(20),11(12)-dien-5-alpha-ol O-acetyltransferase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.3.1.162
BRENDA Enzyme Link: BRENDA 2.3.1.162
KEGG Enzyme Link: KEGG2.3.1.162
BioCyc Enzyme Link: BioCyc 2.3.1.162
ExPASy Enzyme Link: ExPASy2.3.1.162
EC2PDB Enzyme Link: EC2PDB 2.3.1.162
ExplorEnz Enzyme Link: ExplorEnz 2.3.1.162
PRIAM enzyme-specific profiles Link: PRIAM 2.3.1.162
IntEnz Enzyme Link: IntEnz 2.3.1.162
MEDLINE Enzyme Link: MEDLINE 2.3.1.162
MSA:

2.3.1.162;

Phylogenetic Tree:

2.3.1.162;

Uniprot:
M-CSA:
RHEA:22028 acetyl-CoA + taxa-4(20),11-dien-5alpha-ol = CoA + taxa-4(20),11-dien-5alpha-yl acetate
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]=[C;H0;+0:4](-[*:5])-[S;H0;+0:6]-[*:7]>>[*:7]-[SH;+0:6].[*:3]=[C;H0;+0:4](-[*:5])-[O;H0;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Regioselectivity of taxoid-O-acetyltransferases: heterologous expression and characterization of a new taxadien-5alpha-ol-O-acetyltransferase.Chau M, Walker K, Long R, Croteau R2004 Oct 1515369823
Taxol biosynthetic genes.Walker K, Croteau R2001 Sep11524108
Molecular cloning of a taxa-4(20),11(12)-dien-5alpha-ol-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli.Walker K, Schoendorf A, Croteau R2000 Feb 1510666320