EC number:2.3.1.168

Enzyme

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     2. Transferases
        2.3 Acyltransferases
            2.3.1 Transferring groups other than aminoacyl groups
ID:2.3.1.168
Description:Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase.
Alternative Name: Dihydrolipoyl transacylase.
Cath: 3.30.559.10; 4.10.320.10; 3.40.50.920; 3.40.50.970; 2.40.50.100;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.3.1.168
BRENDA Enzyme Link: BRENDA 2.3.1.168
KEGG Enzyme Link: KEGG2.3.1.168
BioCyc Enzyme Link: BioCyc 2.3.1.168
ExPASy Enzyme Link: ExPASy2.3.1.168
EC2PDB Enzyme Link: EC2PDB 2.3.1.168
ExplorEnz Enzyme Link: ExplorEnz 2.3.1.168
PRIAM enzyme-specific profiles Link: PRIAM 2.3.1.168
IntEnz Enzyme Link: IntEnz 2.3.1.168
MEDLINE Enzyme Link: MEDLINE 2.3.1.168

EC number:2.3.1.168

MSA:

2.3.1.168;
Phylogenetic Tree:

2.3.1.168;
Uniprot:
M-CSA:
RHEA:18865 (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + 2-methylpropanoyl-CoA = (R)-N(6)-(S(8)-2-methylpropanoyldihydrolipoyl)-L-lysyl-[protein] + CoA
RULE(radius=1) [*:1]-[SH;+0:2].[*:3]=[C;H0;+0:4](-[*:5])-[S;H0;+0:6]-[*:7]>>[*:7]-[SH;+0:6].[*:3]=[C;H0;+0:4](-[*:5])-[S;H0;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Branched-chain amino acid catabolism in bacteria.Massey LK, Sokatch JR, Conrad RS1976 Mar773366
Catalytic and structural properties of the dihydrolipoyl transacylase component of bovine branched-chain alpha-keto acid dehydrogenase.Chuang DT, Hu CC, Ku LS, Niu WL, Myers DE, Cox RP1984 Jul 256746648
Swinging arms and swinging domains in multifunctional enzymes: catalytic machines for multistep reactions.Perham RN200010966480