EC number:2.3.1.179

Enzyme

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EC Tree
     2. Transferases
        2.3 Acyltransferases
            2.3.1 Transferring groups other than aminoacyl groups
ID:2.3.1.179
Description:Beta-ketoacyl-[acyl-carrier-protein] synthase II.
Alternative Name: KASII.
KAS II.
Beta-ketoacyl-ACP synthase II.
3-oxoacyl-acyl carrier protein synthase I.
Prosite: PDOC00529;
PDB:
PDBScop
Cath: 1.10.1200.10; 1.10.1470.20; 1.10.287.1960; 1.10.287.3150; 1.20.5.3640; 3.30.70.2490; 3.30.70.250; 3.30.70.3290; 3.40.50.720; 3.90.180.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.3.1.179
BRENDA Enzyme Link: BRENDA 2.3.1.179
KEGG Enzyme Link: KEGG2.3.1.179
BioCyc Enzyme Link: BioCyc 2.3.1.179
ExPASy Enzyme Link: ExPASy2.3.1.179
EC2PDB Enzyme Link: EC2PDB 2.3.1.179
ExplorEnz Enzyme Link: ExplorEnz 2.3.1.179
PRIAM enzyme-specific profiles Link: PRIAM 2.3.1.179
IntEnz Enzyme Link: IntEnz 2.3.1.179
MEDLINE Enzyme Link: MEDLINE 2.3.1.179

EC number:2.3.1.179

MSA:

2.3.1.179;
Phylogenetic Tree:

2.3.1.179;
Uniprot:
M-CSA:
RHEA:14565 (11Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(13Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]
RULE(radius=1) [*:1]-[CH2;+0:2]-[C;H0;+0:3](=[*:4])-[OH;+0:5].[*:6]-[S;H0;+0:7]-[C;H0;+0:8](=[*:9])-[*:10].[H+;H0:11]>>[*:6]-[SH;+0:7].[*:9]=[C;H0;+0:8](-[*:10])-[CH2;+0:2]-[*:1].[*:4]=[C;H0;+0:3]=[O;H0;+0:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Cloning of the fabF gene in an expression vector and in vitro characterization of recombinant fabF and fabB encoded enzymes from Escherichia coli.Edwards P, Nelsen JS, Metz JG, Dehesh K1997 Jan 279013860
Structural, enzymatic, and genetic studies of beta-ketoacyl-acyl carrier protein synthases I and II of Escherichia coli.Garwin JL, Klages AL, Cronan JE Jr1980 Dec 257002930
Multiple forms of beta-ketoacyl-acyl carrier protein synthetase in Escherichia coli.D'Agnolo G, Rosenfeld IS, Vagelos PR1975 Jul 25237914
The putative fabJ gene of Escherichia coli fatty acid synthesis is the fabF gene.Magnuson K, Carey MR, Cronan JE Jr1995 Jun7768872
Beta-ketoacyl-acyl carrier protein synthase II of Escherichia coli. Evidence for function in the thermal regulation of fatty acid synthesis.Garwin JL, Klages AL, Cronan JE Jr1980 Apr 256988423