EC number:2.3.1.181
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.3 Acyltransferases |
| 2.3.1 Transferring groups other than aminoacyl groups |
| ID: | 2.3.1.181 | ||||||||||||
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| Description: | Lipoyl(octanoyl) transferase. | ||||||||||||
| Alternative Name: |
Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase. Lipoyltransferase. Lipoyl(octanoyl)transferase. Lipoyl (octanoyl)-[acyl-carrier-protein]-protein N-lipoyltransferase. Lipoate/octanoate transferase. | ||||||||||||
| Prosite: | PDOC01017; | ||||||||||||
| PDB: |
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| Cath: | 3.30.930.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.3.1.181 |
| BRENDA Enzyme Link: | BRENDA 2.3.1.181 |
| KEGG Enzyme Link: | KEGG2.3.1.181 |
| BioCyc Enzyme Link: | BioCyc 2.3.1.181 |
| ExPASy Enzyme Link: | ExPASy2.3.1.181 |
| EC2PDB Enzyme Link: | EC2PDB 2.3.1.181 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.3.1.181 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.3.1.181 |
| IntEnz Enzyme Link: | IntEnz 2.3.1.181 |
| MEDLINE Enzyme Link: | MEDLINE 2.3.1.181 |
EC number:2.3.1.181
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:17665 | L-lysyl-[protein] + octanoyl-[ACP] = H(+) + holo-[ACP] + N(6)-octanoyl-L-lysyl-[protein] |
| RULE(radius=1) | [*:1]-[NH2;+0:2].[*:3]-[S;H0;+0:4]-[C;H0;+0:5](=[*:6])-[*:7]>>[*:3]-[SH;+0:4].[*:6]=[C;H0;+0:5](-[*:7])-[NH;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Expression, purification, and physical characterization of Escherichia coli lipoyl(octanoyl)transferase. | Nesbitt NM, Baleanu-Gogonea C, Cicchillo RM, Goodson K, Iwig DF, Broadwater JA, Haas JA, Fox BG, Booker SJ | 2005 Feb | 15642479 |
| A new metabolic link. The acyl carrier protein of lipid synthesis donates lipoic acid to the pyruvate dehydrogenase complex in Escherichia coli and mitochondria. | Jordan SW, Cronan JE Jr | 1997 Jul 18 | 9218413 |
| Assembly of the covalent linkage between lipoic acid and its cognate enzymes. | Zhao X, Miller JR, Jiang Y, Marletta MA, Cronan JE | 2003 Dec | 14700636 |
| The reaction of LipB, the octanoyl-[acyl carrier protein]:protein N-octanoyltransferase of lipoic acid synthesis, proceeds through an acyl-enzyme intermediate. | Zhao X, Miller JR, Cronan JE | 2005 Dec 20 | 16342964 |