Enzyme

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EC Tree
     2. Transferases
        2.3 Acyltransferases
            2.3.1 Transferring groups other than aminoacyl groups
ID:2.3.1.185
Description:Tropine acyltransferase.
Alternative Name: Tropine tigloyltransferase.
Tropine acetyltransferase.
TAT.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.3.1.185
BRENDA Enzyme Link: BRENDA 2.3.1.185
KEGG Enzyme Link: KEGG2.3.1.185
BioCyc Enzyme Link: BioCyc 2.3.1.185
ExPASy Enzyme Link: ExPASy2.3.1.185
EC2PDB Enzyme Link: EC2PDB 2.3.1.185
ExplorEnz Enzyme Link: ExplorEnz 2.3.1.185
PRIAM enzyme-specific profiles Link: PRIAM 2.3.1.185
IntEnz Enzyme Link: IntEnz 2.3.1.185
MEDLINE Enzyme Link: MEDLINE 2.3.1.185
MSA:

2.3.1.185;

Phylogenetic Tree:

2.3.1.185;

Uniprot:
M-CSA:
RHEA:25516 an acyl-CoA + tropine = CoA + H(+) + O-acyltropine
RULE(radius=1) [*:1]-[C;H0;+0:2](=[*:3])-[S;H0;+0:4]-[*:5].[*:6]-[OH;+0:7]>>[*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:7]-[*:6].[*:5]-[SH;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Functional genomic analysis of alkaloid biosynthesis in Hyoscyamus niger reveals a cytochrome P450 involved in littorine rearrangement.Li R, Reed DW, Liu E, Nowak J, Pelcher LE, Page JE, Covello PS2006 May16720272
The formation of 3 alpha- and 3 beta-acetoxytropanes by Datura stramonium transformed root cultures involves two acetyl-CoA-dependent acyltransferases.Robins RJ, Bachmann P, Robinson T, Rhodes MJ, Yamada Y1991 Nov 41959620
Specificities of the enzymes of N-alkyltropane biosynthesis in Brugmansia and Datura.Boswell HD, Dräger B, McLauchlan WR, Portsteffen A, Robins DJ, Robins RJ, Walton NJ1999 Nov10626376