EC number:2.3.1.194

Enzyme

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EC Tree
     2. Transferases
        2.3 Acyltransferases
            2.3.1 Transferring groups other than aminoacyl groups
ID:2.3.1.194
Description:Acetoacetyl-CoA synthase.
Alternative Name: NphT7.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.3.1.194
BRENDA Enzyme Link: BRENDA 2.3.1.194
KEGG Enzyme Link: KEGG2.3.1.194
BioCyc Enzyme Link: BioCyc 2.3.1.194
ExPASy Enzyme Link: ExPASy2.3.1.194
EC2PDB Enzyme Link: EC2PDB 2.3.1.194
ExplorEnz Enzyme Link: ExplorEnz 2.3.1.194
PRIAM enzyme-specific profiles Link: PRIAM 2.3.1.194
IntEnz Enzyme Link: IntEnz 2.3.1.194
MEDLINE Enzyme Link: MEDLINE 2.3.1.194

EC number:2.3.1.194

MSA:

2.3.1.194;
Phylogenetic Tree:

2.3.1.194;
Uniprot:
M-CSA:
RHEA:28250 acetyl-CoA + H(+) + malonyl-CoA = acetoacetyl-CoA + CO2 + CoA
RULE(radius=1) [C:1][S:2][C:3](=[O:4])[*:5].[C:6][S:7][C:8](=[O:9])[C:10][C:11](=[O:12])[O:13]>>[C:1][SH:2].[O+0:13]=[C:11]=[O:12].[C:6][S:7][C:8](=[O:9])[C:10][C:3](=[O:4])[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Unprecedented acetoacetyl-coenzyme A synthesizing enzyme of the thiolase superfamily involved in the mevalonate pathway.Okamura E, Tomita T, Sawa R, Nishiyama M, Kuzuyama T2010 Jun 2220534558