EC number:2.3.1.20
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.3 Acyltransferases |
| 2.3.1 Transferring groups other than aminoacyl groups |
| ID: | 2.3.1.20 |
|---|---|
| Description: | Diacylglycerol O-acyltransferase. |
| Alternative Name: |
Diglyceride acyltransferase. |
| Cath: | 3.40.50.1820; |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 2.3.1.20 |
| BRENDA Enzyme Link: | BRENDA 2.3.1.20 |
| KEGG Enzyme Link: | KEGG2.3.1.20 |
| BioCyc Enzyme Link: | BioCyc 2.3.1.20 |
| ExPASy Enzyme Link: | ExPASy2.3.1.20 |
| EC2PDB Enzyme Link: | EC2PDB 2.3.1.20 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.3.1.20 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.3.1.20 |
| IntEnz Enzyme Link: | IntEnz 2.3.1.20 |
| MEDLINE Enzyme Link: | MEDLINE 2.3.1.20 |
| RHEA:10868 | a 1,2-diacyl-sn-glycerol + an acyl-CoA = a triacyl-sn-glycerol + CoA |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](=[*:3])-[S;H0;+0:4]-[*:5].[*:6]-[OH;+0:7]>>[*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:7]-[*:6].[*:5]-[SH;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Characterization of two human genes encoding acyl coenzyme A:cholesterol acyltransferase-related enzymes. | Oelkers P, Behari A, Cromley D, Billheimer JT, Sturley SL | 1998 Oct 9 | 9756920 |
| A novel diacylglycerol acyltransferase (DGAT2) is decreased in human psoriatic skin and increased in diabetic mice. | Wakimoto K, Chiba H, Michibata H, Seishima M, Kawasaki S, Okubo K, Mitsui H, Torii H, Imai Y | 2003 Oct 17 | 14521909 |
| Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members. | Cases S, Stone SJ, Zhou P, Yen E, Tow B, Lardizabal KD, Voelker T, Farese RV Jr | 2001 Oct 19 | 11481335 |