EC number:2.3.1.211
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.3 Acyltransferases |
| 2.3.1 Transferring groups other than aminoacyl groups |
| ID: | 2.3.1.211 |
|---|---|
| Description: | Bisdemethoxycurcumin synthase. |
| Alternative Name: |
Curcuminoid synthase. |
| Cath: | 3.40.47.10; |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 2.3.1.211 |
| BRENDA Enzyme Link: | BRENDA 2.3.1.211 |
| KEGG Enzyme Link: | KEGG2.3.1.211 |
| BioCyc Enzyme Link: | BioCyc 2.3.1.211 |
| ExPASy Enzyme Link: | ExPASy2.3.1.211 |
| EC2PDB Enzyme Link: | EC2PDB 2.3.1.211 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.3.1.211 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.3.1.211 |
| IntEnz Enzyme Link: | IntEnz 2.3.1.211 |
| MEDLINE Enzyme Link: | MEDLINE 2.3.1.211 |
EC number:2.3.1.211
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:34803 | 2 4-coumaroyl-CoA + H(+) + H2O + malonyl-CoA = bisdemethoxycurcumin + 2 CO2 + 3 CoA |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](=[*:3])-[S;H0;+0:4]-[*:5].[*:6]=[C;H0;+0:7](-[*:8])-[S;H0;+0:9]-[*:10].[*:11]=[C;H0;+0:12](-[OH;+0:13])-[CH2;+0:14]-[C;H0;+0:15](=[*:16])-[S;H0;+0:17]-[*:18].[H+;H0:19].[OH2;+0:20]>>[*:1]-[C;H0;+0:2](=[*:3])-[CH2;+0:14]-[C;H0;+0:7](=[*:6])-[*:8].[*:18]-[SH;+0:17].[*:10]-[SH;+0:9].[*:5]-[SH;+0:4].[*:11]=[C;H0;+0:12]=[O;H0;+0:13].[*:16]=[C;H0;+0:15]=[O;H0;+0:20] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Crystal structure of curcuminoid synthase CUS from Oryza sativa. | Miyazono K, Um J, Imai FL, Katsuyama Y, Ohnishi Y, Horinouchi S, Tanokura M | 2011 Feb | 21117241 |
| Structural basis for the one-pot formation of the diarylheptanoid scaffold by curcuminoid synthase from Oryza sativa. | Morita H, Wanibuchi K, Nii H, Kato R, Sugio S, Abe I | 2010 Nov 16 | 21041675 |
| Production of dehydrogingerdione derivatives in Escherichia coli by exploiting a curcuminoid synthase from Oryza sativa and a β-oxidation pathway from Saccharomyces cerevisiae. | Katsuyama Y, Ohnishi Y, Horinouchi S | 2010 Sep 24 | 20836122 |
| Expression, purification and crystallization of a plant type III polyketide synthase that produces diarylheptanoids. | Morita H, Wanibuchi K, Kato R, Sugio S, Abe I | 2010 Aug 1 | 20693677 |
| Production of curcuminoids by Escherichia coli carrying an artificial biosynthesis pathway. | Katsuyama Y, Matsuzawa M, Funa N, Horinouchi S | 2008 Sep | 18757796 |
| In vitro synthesis of curcuminoids by type III polyketide synthase from Oryza sativa. | Katsuyama Y, Matsuzawa M, Funa N, Horinouchi S | 2007 Dec 28 | 17932040 |