| EC Tree |
| 2. Transferases |
| 2.3 Acyltransferases |
| 2.3.1 Transferring groups other than aminoacyl groups |
| ID: | 2.3.1.218 |
|---|---|
| Description: | Phenylpropanoylacetyl-CoA synthase. |
| Alternative Name: |
Phenylpropanoyl-diketide-CoA synthase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 2.3.1.218 |
| BRENDA Enzyme Link: | BRENDA 2.3.1.218 |
| KEGG Enzyme Link: | KEGG2.3.1.218 |
| BioCyc Enzyme Link: | BioCyc 2.3.1.218 |
| ExPASy Enzyme Link: | ExPASy2.3.1.218 |
| EC2PDB Enzyme Link: | EC2PDB 2.3.1.218 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.3.1.218 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.3.1.218 |
| IntEnz Enzyme Link: | IntEnz 2.3.1.218 |
| MEDLINE Enzyme Link: | MEDLINE 2.3.1.218 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:35115 | 4-coumaroyl-CoA + H(+) + malonyl-CoA = (4-coumaroyl)acetyl-CoA + CO2 + CoA |
| RULE(radius=1) | [*:1]=[C;H0;+0:2](-[*:3])-[S;H0;+0:4]-[*:5].[*:6]=[C;H0;+0:7](-[OH;+0:8])-[CH2;+0:9]-[*:10].[H+;H0:11]>>[*:5]-[SH;+0:4].[*:1]=[C;H0;+0:2](-[*:3])-[CH2;+0:9]-[*:10].[*:6]=[C;H0;+0:7]=[O;H0;+0:8] |
| Reaction | ![]() |
| Core-to-Core | |
| Core-to-Core | |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Curcuminoid biosynthesis by two type III polyketide synthases in the herb Curcuma longa. | Katsuyama Y, Kita T, Funa N, Horinouchi S | 2009 Apr 24 | 19258320 |
| RHEA:22500 | feruloyl-CoA + H(+) + malonyl-CoA = CO2 + CoA + feruloylacetyl-CoA |
| RULE(radius=1) | [*:1]=[C;H0;+0:2](-[*:3])-[S;H0;+0:4]-[*:5].[*:6]=[C;H0;+0:7](-[OH;+0:8])-[CH2;+0:9]-[*:10].[H+;H0:11]>>[*:5]-[SH;+0:4].[*:1]=[C;H0;+0:2](-[*:3])-[CH2;+0:9]-[*:10].[*:6]=[C;H0;+0:7]=[O;H0;+0:8] |
| Reaction | ![]() |
| Core-to-Core | |
| Core-to-Core | |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Identification and characterization of multiple curcumin synthases from the herb Curcuma longa. | Katsuyama Y, Kita T, Horinouchi S | 2009 Sep 3 | 19622354 |
| Benzalacetone synthase. A novel polyketide synthase that plays a crucial role in the biosynthesis of phenylbutanones in Rheum palmatum. | Abe I, Takahashi Y, Morita H, Noguchi H | 2001 Jun | 11389739 |