| EC Tree |
| 2. Transferases |
| 2.3 Acyltransferases |
| 2.3.1 Transferring groups other than aminoacyl groups |
| ID: | 2.3.1.228 |
|---|---|
| Description: | Isovaleryl-homoserine lactone synthase. |
| Alternative Name: |
IV-HSL synthase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 2.3.1.228 |
| BRENDA Enzyme Link: | BRENDA 2.3.1.228 |
| KEGG Enzyme Link: | KEGG2.3.1.228 |
| BioCyc Enzyme Link: | BioCyc 2.3.1.228 |
| ExPASy Enzyme Link: | ExPASy2.3.1.228 |
| EC2PDB Enzyme Link: | EC2PDB 2.3.1.228 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.3.1.228 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.3.1.228 |
| IntEnz Enzyme Link: | IntEnz 2.3.1.228 |
| MEDLINE Enzyme Link: | MEDLINE 2.3.1.228 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:37471 | 3-methylbutanoyl-CoA + S-adenosyl-L-methionine = CoA + H(+) + N-isovaleryl-L-homoserine lactone + S-methyl-5'-thioadenosine |
| RULE(radius=1) | [*:1]-[S+;H0:2](-[*:3])-[CH2;+0:4]-[*:5]-[*:6](-[NH2;+0:7])-[*:8]-[OH;+0:9].[*:10]=[C;H0;+0:11](-[*:12])-[S;H0;+0:13]-[*:14]>>[*:1]-[S;H0;+0:2]-[*:3].[*:14]-[SH;+0:13].[*:10]=[C;H0;+0:11](-[*:12])-[NH;+0:7]-[*:6]1-[*:8]-[O;H0;+0:9]-[CH2;+0:4]-[*:5]-1 |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Isovaleryl-homoserine lactone, an unusual branched-chain quorum-sensing signal from the soybean symbiont Bradyrhizobium japonicum. | Lindemann A, Pessi G, Schaefer AL, Mattmann ME, Christensen QH, Kessler A, Hennecke H, Blackwell HE, Greenberg EP, Harwood CS | 2011 Oct 4 | 21949379 |