Enzyme

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EC Tree
     2. Transferases
        2.3 Acyltransferases
            2.3.1 Transferring groups other than aminoacyl groups
ID:2.3.1.228
Description:Isovaleryl-homoserine lactone synthase.
Alternative Name: IV-HSL synthase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.3.1.228
BRENDA Enzyme Link: BRENDA 2.3.1.228
KEGG Enzyme Link: KEGG2.3.1.228
BioCyc Enzyme Link: BioCyc 2.3.1.228
ExPASy Enzyme Link: ExPASy2.3.1.228
EC2PDB Enzyme Link: EC2PDB 2.3.1.228
ExplorEnz Enzyme Link: ExplorEnz 2.3.1.228
PRIAM enzyme-specific profiles Link: PRIAM 2.3.1.228
IntEnz Enzyme Link: IntEnz 2.3.1.228
MEDLINE Enzyme Link: MEDLINE 2.3.1.228
MSA:

2.3.1.228;

Phylogenetic Tree:

2.3.1.228;

Uniprot:
M-CSA:
RHEA:37471 3-methylbutanoyl-CoA + S-adenosyl-L-methionine = CoA + H(+) + N-isovaleryl-L-homoserine lactone + S-methyl-5'-thioadenosine
RULE(radius=1) [*:1]-[S+;H0:2](-[*:3])-[CH2;+0:4]-[*:5]-[*:6](-[NH2;+0:7])-[*:8]-[OH;+0:9].[*:10]=[C;H0;+0:11](-[*:12])-[S;H0;+0:13]-[*:14]>>[*:1]-[S;H0;+0:2]-[*:3].[*:14]-[SH;+0:13].[*:10]=[C;H0;+0:11](-[*:12])-[NH;+0:7]-[*:6]1-[*:8]-[O;H0;+0:9]-[CH2;+0:4]-[*:5]-1
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Isovaleryl-homoserine lactone, an unusual branched-chain quorum-sensing signal from the soybean symbiont Bradyrhizobium japonicum.Lindemann A, Pessi G, Schaefer AL, Mattmann ME, Christensen QH, Kessler A, Hennecke H, Blackwell HE, Greenberg EP, Harwood CS2011 Oct 421949379