Enzyme

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EC Tree
     2. Transferases
        2.3 Acyltransferases
            2.3.1 Transferring groups other than aminoacyl groups
ID:2.3.1.24
Description:Sphingosine N-acyltransferase.
Cath: 1.10.10.60;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.3.1.24
BRENDA Enzyme Link: BRENDA 2.3.1.24
KEGG Enzyme Link: KEGG2.3.1.24
BioCyc Enzyme Link: BioCyc 2.3.1.24
ExPASy Enzyme Link: ExPASy2.3.1.24
EC2PDB Enzyme Link: EC2PDB 2.3.1.24
ExplorEnz Enzyme Link: ExplorEnz 2.3.1.24
PRIAM enzyme-specific profiles Link: PRIAM 2.3.1.24
IntEnz Enzyme Link: IntEnz 2.3.1.24
MEDLINE Enzyme Link: MEDLINE 2.3.1.24
MSA:

2.3.1.24;

Phylogenetic Tree:

2.3.1.24;

Uniprot:
M-CSA:
RHEA:23768 an acyl-CoA + sphing-4-enine = an N-acylsphing-4-enine + CoA + H(+)
RULE(radius=1) [*:1]-[C;H0;+0:2](=[*:3])-[S;H0;+0:4]-[*:5].[*:6]-[NH2;+0:7]>>[*:1]-[C;H0;+0:2](=[*:3])-[NH;+0:7]-[*:6].[*:5]-[SH;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Protection of C. elegans from anoxia by HYL-2 ceramide synthase.Menuz V, Howell KS, Gentina S, Epstein S, Riezman I, Fornallaz-Mulhauser M, Hengartner MO, Gomez M, Riezman H, Martinou JC2009 Apr 1719372430
LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro)ceramide synthase with relatively broad substrate specificity.Mizutani Y, Kihara A, Igarashi Y2006 Sep 1516753040