| EC Tree |
| 2. Transferases |
| 2.3 Acyltransferases |
| 2.3.1 Transferring groups other than aminoacyl groups |
| ID: | 2.3.1.24 |
|---|---|
| Description: | Sphingosine N-acyltransferase. |
| Cath: | 1.10.10.60; |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 2.3.1.24 |
| BRENDA Enzyme Link: | BRENDA 2.3.1.24 |
| KEGG Enzyme Link: | KEGG2.3.1.24 |
| BioCyc Enzyme Link: | BioCyc 2.3.1.24 |
| ExPASy Enzyme Link: | ExPASy2.3.1.24 |
| EC2PDB Enzyme Link: | EC2PDB 2.3.1.24 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.3.1.24 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.3.1.24 |
| IntEnz Enzyme Link: | IntEnz 2.3.1.24 |
| MEDLINE Enzyme Link: | MEDLINE 2.3.1.24 |
| RHEA:23768 | an acyl-CoA + sphing-4-enine = an N-acylsphing-4-enine + CoA + H(+) |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](=[*:3])-[S;H0;+0:4]-[*:5].[*:6]-[NH2;+0:7]>>[*:1]-[C;H0;+0:2](=[*:3])-[NH;+0:7]-[*:6].[*:5]-[SH;+0:4] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Protection of C. elegans from anoxia by HYL-2 ceramide synthase. | Menuz V, Howell KS, Gentina S, Epstein S, Riezman I, Fornallaz-Mulhauser M, Hengartner MO, Gomez M, Riezman H, Martinou JC | 2009 Apr 17 | 19372430 |
| LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro)ceramide synthase with relatively broad substrate specificity. | Mizutani Y, Kihara A, Igarashi Y | 2006 Sep 15 | 16753040 |