EC number:2.3.1.241

Enzyme

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     2. Transferases
        2.3 Acyltransferases
            2.3.1 Transferring groups other than aminoacyl groups
ID:2.3.1.241
Description:Kdo(2)-lipid IV(A) lauroyltransferase.
Alternative Name: Alpha-Kdo-(2->4)-alpha-(2->6)-lipid IV(A) lauroyltransferase.
(Kdo)(2)-lipid IV(A) lauroyltransferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.3.1.241
BRENDA Enzyme Link: BRENDA 2.3.1.241
KEGG Enzyme Link: KEGG2.3.1.241
BioCyc Enzyme Link: BioCyc 2.3.1.241
ExPASy Enzyme Link: ExPASy2.3.1.241
EC2PDB Enzyme Link: EC2PDB 2.3.1.241
ExplorEnz Enzyme Link: ExplorEnz 2.3.1.241
PRIAM enzyme-specific profiles Link: PRIAM 2.3.1.241
IntEnz Enzyme Link: IntEnz 2.3.1.241
MEDLINE Enzyme Link: MEDLINE 2.3.1.241

EC number:2.3.1.241

MSA:

2.3.1.241;
Phylogenetic Tree:

2.3.1.241;
Uniprot:
M-CSA:
RHEA:28442 alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + dodecanoyl-[ACP] = dodecanoyl-(Kdo)2-lipid IVA + holo-[ACP]
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S;H0;+0:4]-[C;H0;+0:5](=[*:6])-[*:7]>>[*:3]-[SH;+0:4].[*:6]=[C;H0;+0:5](-[*:7])-[O;H0;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Function of the htrB high temperature requirement gene of Escherichia coli in the acylation of lipid A: HtrB catalyzed incorporation of laurate.Clementz T, Bednarski JJ, Raetz CR1996 May 178662613
Biosynthesis of lipid A in Escherichia coli. Acyl carrier protein-dependent incorporation of laurate and myristate.Brozek KA, Raetz CR1990 Sep 152203778
Purification and mutagenesis of LpxL, the lauroyltransferase of Escherichia coli lipid A biosynthesis.Six DA, Carty SM, Guan Z, Raetz CR2008 Aug 1918656959