Enzyme

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     2. Transferases
        2.3 Acyltransferases
            2.3.1 Transferring groups other than aminoacyl groups
ID:2.3.1.243
Description:Lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase.
Alternative Name: (dodecanoyl)-lipid IV(A) O-myristoyltransferase.
Myristoyl-[acyl-carrier protein]:alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.3.1.243
BRENDA Enzyme Link: BRENDA 2.3.1.243
KEGG Enzyme Link: KEGG2.3.1.243
BioCyc Enzyme Link: BioCyc 2.3.1.243
ExPASy Enzyme Link: ExPASy2.3.1.243
EC2PDB Enzyme Link: EC2PDB 2.3.1.243
ExplorEnz Enzyme Link: ExplorEnz 2.3.1.243
PRIAM enzyme-specific profiles Link: PRIAM 2.3.1.243
IntEnz Enzyme Link: IntEnz 2.3.1.243
MEDLINE Enzyme Link: MEDLINE 2.3.1.243
MSA:

2.3.1.243;

Phylogenetic Tree:

2.3.1.243;

Uniprot:
M-CSA:
RHEA:28438 dodecanoyl-(Kdo)2-lipid IVA + tetradecanoyl-[ACP] = alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A + holo-[ACP]
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S;H0;+0:4]-[C;H0;+0:5](=[*:6])-[*:7]>>[*:3]-[SH;+0:4].[*:6]=[C;H0;+0:5](-[*:7])-[O;H0;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Function of the Escherichia coli msbB gene, a multicopy suppressor of htrB knockouts, in the acylation of lipid A. Acylation by MsbB follows laurate incorporation by HtrB.Clementz T, Zhou Z, Raetz CR1997 Apr 189099672