EC number:2.3.1.247

Enzyme

Download
EC Tree
     2. Transferases
        2.3 Acyltransferases
            2.3.1 Transferring groups other than aminoacyl groups
ID:2.3.1.247
Description:3-keto-5-aminohexanoate cleavage enzyme.
Cath: 3.20.20.70;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.
PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.3.1.247
BRENDA Enzyme Link: BRENDA 2.3.1.247
KEGG Enzyme Link: KEGG2.3.1.247
BioCyc Enzyme Link: BioCyc 2.3.1.247
ExPASy Enzyme Link: ExPASy2.3.1.247
EC2PDB Enzyme Link: EC2PDB 2.3.1.247
ExplorEnz Enzyme Link: ExplorEnz 2.3.1.247
PRIAM enzyme-specific profiles Link: PRIAM 2.3.1.247
IntEnz Enzyme Link: IntEnz 2.3.1.247
MEDLINE Enzyme Link: MEDLINE 2.3.1.247

EC number:2.3.1.247

MSA:

2.3.1.247;
Phylogenetic Tree:

2.3.1.247;
Uniprot:
M-CSA:
RHEA:31555 (5S)-5-amino-3-oxo-hexanoate + acetyl-CoA = (3S)-3-aminobutanoyl-CoA + acetoacetate
RULE(radius=1) [*:1]-[CH2;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[CH3;+0:7]>>[*:6]-[CH2;+0:7]-[CH;+0:3](-[*:4])-[*:5].[*:1]-[CH3;+0:2]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Pathway of lysine degradation in Fusobacterium nucleatum.Barker HA, Kahn JM, Hedrick L1982 Oct6811551
3-Keto-5-aminohexanoate cleavage enzyme: a common fold for an uncommon Claisen-type condensation.Bellinzoni M, Bastard K, Perret A, Zaparucha A, Perchat N, Vergne C, Wagner T, de Melo-Minardi RC, Artiguenave F, Cohen GN, Weissenbach J, Salanoubat M, Alzari PM2011 Aug 521632536
Identification of the last unknown genes in the fermentation pathway of lysine.Kreimeyer A, Perret A, Lechaplais C, Vallenet D, Médigue C, Salanoubat M, Weissenbach J2007 Mar 917166837