Enzyme

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     2. Transferases
        2.3 Acyltransferases
            2.3.1 Transferring groups other than aminoacyl groups
ID:2.3.1.251
Description:Lipid IV(A) palmitoyltransferase.
Cath: 2.40.160.20;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.3.1.251
BRENDA Enzyme Link: BRENDA 2.3.1.251
KEGG Enzyme Link: KEGG2.3.1.251
BioCyc Enzyme Link: BioCyc 2.3.1.251
ExPASy Enzyme Link: ExPASy2.3.1.251
EC2PDB Enzyme Link: EC2PDB 2.3.1.251
ExplorEnz Enzyme Link: ExplorEnz 2.3.1.251
PRIAM enzyme-specific profiles Link: PRIAM 2.3.1.251
IntEnz Enzyme Link: IntEnz 2.3.1.251
MEDLINE Enzyme Link: MEDLINE 2.3.1.251
MSA:

2.3.1.251;

Phylogenetic Tree:

2.3.1.251;

Uniprot:
M-CSA:
RHEA:46872 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + lipid IIA = a 2-acyl-sn-glycero-3-phosphocholine + lipid IIB
RULE(radius=1) [*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:4]-[*:5].[*:6]-[OH;+0:7]>>[*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:7]-[*:6].[*:5]-[OH;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
PagP crystallized from SDS/cosolvent reveals the route for phospholipid access to the hydrocarbon ruler.Cuesta-Seijo JA, Neale C, Khan MA, Moktar J, Tran CD, Bishop RE, Pomès R, Privé GG2010 Sep 820826347
Transfer of palmitate from phospholipids to lipid A in outer membranes of gram-negative bacteria.Bishop RE, Gibbons HS, Guina T, Trent MS, Miller SI, Raetz CR2000 Oct 211013210

RHEA:46868 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + lipid IVA (E. coli) = a 2-acyl-sn-glycero-3-phosphocholine + lipid IVB
RULE(radius=1) [*:1]-[O;H0;+0:2]-[C;H0;+0:3](=[*:4])-[*:5].([*:6]-[OH;+0:7].[*:8]=[P;H0;+0:9](-[*:10])(-[*:11])-[O;H0;+0:12]-[*:13]-[O;H0;+0:14]-[CH;+0:15](-[*:16])-[*:17])>>[*:1]-[OH;+0:2].([*:4]=[C;H0;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:8]=[P;H0;+0:9](-[*:10])(-[*:11])-[O;H0;+0:14]-[*:13]-[O;H0;+0:12]-[CH;+0:15](-[*:16])-[*:17])
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
PagP crystallized from SDS/cosolvent reveals the route for phospholipid access to the hydrocarbon ruler.Cuesta-Seijo JA, Neale C, Khan MA, Moktar J, Tran CD, Bishop RE, Pomès R, Privé GG2010 Sep 820826347
Transfer of palmitate from phospholipids to lipid A in outer membranes of gram-negative bacteria.Bishop RE, Gibbons HS, Guina T, Trent MS, Miller SI, Raetz CR2000 Oct 211013210

RHEA:46864 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + lipid A (E. coli) = a 2-acyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A
RULE(radius=1) [*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:4]-[*:5].[*:6]-[OH;+0:7]>>[*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:7]-[*:6].[*:5]-[OH;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
PagP crystallized from SDS/cosolvent reveals the route for phospholipid access to the hydrocarbon ruler.Cuesta-Seijo JA, Neale C, Khan MA, Moktar J, Tran CD, Bishop RE, Pomès R, Privé GG2010 Sep 820826347
Transfer of palmitate from phospholipids to lipid A in outer membranes of gram-negative bacteria.Bishop RE, Gibbons HS, Guina T, Trent MS, Miller SI, Raetz CR2000 Oct 211013210