| EC Tree |
| 2. Transferases |
| 2.3 Acyltransferases |
| 2.3.1 Transferring groups other than aminoacyl groups |
| ID: | 2.3.1.251 |
|---|---|
| Description: | Lipid IV(A) palmitoyltransferase. |
| Cath: | 2.40.160.20; |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 2.3.1.251 |
| BRENDA Enzyme Link: | BRENDA 2.3.1.251 |
| KEGG Enzyme Link: | KEGG2.3.1.251 |
| BioCyc Enzyme Link: | BioCyc 2.3.1.251 |
| ExPASy Enzyme Link: | ExPASy2.3.1.251 |
| EC2PDB Enzyme Link: | EC2PDB 2.3.1.251 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.3.1.251 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.3.1.251 |
| IntEnz Enzyme Link: | IntEnz 2.3.1.251 |
| MEDLINE Enzyme Link: | MEDLINE 2.3.1.251 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:46872 | 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + lipid IIA = a 2-acyl-sn-glycero-3-phosphocholine + lipid IIB |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:4]-[*:5].[*:6]-[OH;+0:7]>>[*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:7]-[*:6].[*:5]-[OH;+0:4] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| PagP crystallized from SDS/cosolvent reveals the route for phospholipid access to the hydrocarbon ruler. | Cuesta-Seijo JA, Neale C, Khan MA, Moktar J, Tran CD, Bishop RE, Pomès R, Privé GG | 2010 Sep 8 | 20826347 |
| Transfer of palmitate from phospholipids to lipid A in outer membranes of gram-negative bacteria. | Bishop RE, Gibbons HS, Guina T, Trent MS, Miller SI, Raetz CR | 2000 Oct 2 | 11013210 |
| RHEA:46868 | 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + lipid IVA (E. coli) = a 2-acyl-sn-glycero-3-phosphocholine + lipid IVB |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[C;H0;+0:3](=[*:4])-[*:5].([*:6]-[OH;+0:7].[*:8]=[P;H0;+0:9](-[*:10])(-[*:11])-[O;H0;+0:12]-[*:13]-[O;H0;+0:14]-[CH;+0:15](-[*:16])-[*:17])>>[*:1]-[OH;+0:2].([*:4]=[C;H0;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:8]=[P;H0;+0:9](-[*:10])(-[*:11])-[O;H0;+0:14]-[*:13]-[O;H0;+0:12]-[CH;+0:15](-[*:16])-[*:17]) |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| PagP crystallized from SDS/cosolvent reveals the route for phospholipid access to the hydrocarbon ruler. | Cuesta-Seijo JA, Neale C, Khan MA, Moktar J, Tran CD, Bishop RE, Pomès R, Privé GG | 2010 Sep 8 | 20826347 |
| Transfer of palmitate from phospholipids to lipid A in outer membranes of gram-negative bacteria. | Bishop RE, Gibbons HS, Guina T, Trent MS, Miller SI, Raetz CR | 2000 Oct 2 | 11013210 |
| RHEA:46864 | 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + lipid A (E. coli) = a 2-acyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:4]-[*:5].[*:6]-[OH;+0:7]>>[*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:7]-[*:6].[*:5]-[OH;+0:4] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| PagP crystallized from SDS/cosolvent reveals the route for phospholipid access to the hydrocarbon ruler. | Cuesta-Seijo JA, Neale C, Khan MA, Moktar J, Tran CD, Bishop RE, Pomès R, Privé GG | 2010 Sep 8 | 20826347 |
| Transfer of palmitate from phospholipids to lipid A in outer membranes of gram-negative bacteria. | Bishop RE, Gibbons HS, Guina T, Trent MS, Miller SI, Raetz CR | 2000 Oct 2 | 11013210 |