EC number:2.3.1.26
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.3 Acyltransferases |
| 2.3.1 Transferring groups other than aminoacyl groups |
| ID: | 2.3.1.26 |
|---|---|
| Description: | Sterol O-acyltransferase. |
| Alternative Name: |
Sterol-ester synthase. Cholesterol acyltransferase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.3.1.26 |
| BRENDA Enzyme Link: | BRENDA 2.3.1.26 |
| KEGG Enzyme Link: | KEGG2.3.1.26 |
| BioCyc Enzyme Link: | BioCyc 2.3.1.26 |
| ExPASy Enzyme Link: | ExPASy2.3.1.26 |
| EC2PDB Enzyme Link: | EC2PDB 2.3.1.26 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.3.1.26 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.3.1.26 |
| IntEnz Enzyme Link: | IntEnz 2.3.1.26 |
| MEDLINE Enzyme Link: | MEDLINE 2.3.1.26 |
| RHEA:17729 | an acyl-CoA + cholesterol = a cholesterol ester + CoA |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](=[*:3])-[S;H0;+0:4]-[*:5].[*:6]-[OH;+0:7]>>[*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:7]-[*:6].[*:5]-[SH;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Functionality of the seventh and eighth transmembrane domains of acyl-coenzyme A:cholesterol acyltransferase 1. | Guo ZY, Chang CC, Chang TY | 2007 Sep 4 | 17691824 |
| The active site His-460 of human acyl-coenzyme A:cholesterol acyltransferase 1 resides in a hitherto undisclosed transmembrane domain. | Guo ZY, Lin S, Heinen JA, Chang CC, Chang TY | 2005 Nov 11 | 16154994 |
| Acyl coenzyme A: cholesterol acyltransferase types 1 and 2: structure and function in atherosclerosis. | Rudel LL, Lee RG, Cockman TL | 2001 Apr | 11264983 |